Browse EV MemProt Atlas
Supporting publications (n)

Number of publications supporting the inclusion of this protein in EV MemProt Atlas.

EVMP confidence score

Annotation confidence score; open for threshold definitions.

Extremely high >= 0.85High >= 0.70Medium >= 0.55Low >= 0.40
UniProt IDProtein namesProtein classificationTransmembrane countRelated DiseasesMediation categoriesDownload
PPBTP05186Alkaline phosphatase, tissue-nonspecific isozyme (AP-TNAP) (TNS-ALP) (TNSALP) (EC 3.1.3.1) (Alkaline phosphatase liver/bone/kidney isozyme) (Phosphoamidase) (Phosphocreatine phosphatase) (EC 3.9.1.1)Cancer-related genesDisease related genesEnzymesColon cancerGenetic prion diseaseMineral absorption/transport disorderClinical-translation mediationImmune mediationMetabolism mediation140.47
TSN8P19075Tetraspanin-8 (Tspan-8) (Transmembrane 4 superfamily member 3) (Tumor-associated antigen CO-029)Cancer-related genesPredicted membrane proteins4Immune mediation140.47
ADCY6O43306Adenylate cyclase type 6 (EC 4.6.1.1) (ATP pyrophosphate-lyase 6) (Adenylate cyclase type VI) (Adenylyl cyclase 6) (Ca(2+)-inhibitable adenylyl cyclase)Disease related genesEnzymesHuman disease related genes12Clinical-translation mediationFusion and delivery mediationMetabolism mediation120.47
CAD11P55287Cadherin-11 (OSF-4) (Osteoblast cadherin) (OB-cadherin)Cancer-related genesDisease related genesHuman disease related genes1Rheumatoid arthritisAdhesion and uptake mediationClinical-translation mediationFusion and delivery mediation120.47
CD22P20273B-cell receptor CD22 (B-lymphocyte cell adhesion molecule) (BL-CAM) (Sialic acid-binding Ig-like lectin 2) (Siglec-2) (T-cell surface antigen Leu-14) (CD antigen CD22)CD markersFDA approved drug targetsPlasma proteins1Acute myeloid leukaemiaB-cell lymphomaDiabetes mellitusClinical-translation mediationFusion and delivery mediationImmune mediation120.47
CAD17Q12864Cadherin-17 (Intestinal peptide-associated transporter HPT-1) (Liver-intestine cadherin) (LI-cadherin)Cancer-related genesPlasma proteinsPredicted intracellular proteins1Adhesion and uptake mediationFusion and delivery mediationImmune mediation110.47
FGFR3P22607Fibroblast growth factor receptor 3 (FGFR-3) (EC 2.7.10.1) (CD antigen CD333)Cancer-related genesCD markersDisease related genes1Alzheimer diseaseBladder cancerBreast cancerAdhesion and uptake mediationClinical-translation mediationFusion and delivery mediation110.47
SEM7AO75326Semaphorin-7A (CDw108) (JMH blood group antigen) (John-Milton-Hargen human blood group Ag) (Semaphorin-K1) (Sema K1) (Semaphorin-L) (Sema L) (CD antigen CD108)Blood group antigen proteinsCD markersDisease related genesFusion and delivery mediationImmune mediationReceptor-signaling mediation100.38
CXCR1P25024C-X-C chemokine receptor type 1 (CXC-R1) (CXCR-1) (CDw128a) (High affinity interleukin-8 receptor A) (IL-8R A) (IL-8 receptor type 1) (CD antigen CD181)Cancer-related genesCD markersG-protein coupled receptors7Chronic obstructive pulmonary diseaseGoutIndeterminate colitisAdhesion and uptake mediationClinical-translation mediationFusion and delivery mediation90.38
SC6A6P31641Sodium- and chloride-dependent taurine transporter (Solute carrier family 6 member 6) (Taurine transporter) (TauT)Disease related genesMetabolic proteinsPotential drug targets12Clinical-translation mediationFusion and delivery mediation90.38
CEAM6P40199Cell adhesion molecule CEACAM6 (Carcinoembryonic antigen-related cell adhesion molecule 6) (CEA cell adhesion molecule 6) (Non-specific crossreacting antigen) (Normal cross-reacting antigen) (CD antigen CD66c)Cancer-related genesCD markersPredicted intracellular proteinsAdhesion and uptake mediationFusion and delivery mediationImmune mediation80.38
CLN3Q13286Battenin (Batten disease protein) (Protein CLN3)Disease related genesHuman disease related genesPotential drug targets6Lysosomal diseaseAdhesion and uptake mediationClinical-translation mediationFusion and delivery mediation80.38
CR2P20023Complement receptor type 2 (Cr2) (Complement C3d receptor) (Epstein-Barr virus receptor) (EBV receptor) (CD antigen CD21)CD markersDisease related genesHuman disease related genes1Immune mediation80.38
CD19P15391B-lymphocyte antigen CD19 (B-lymphocyte surface antigen B4) (Differentiation antigen CD19) (T-cell surface antigen Leu-12) (CD antigen CD19)CD markersDisease related genesFDA approved drug targets1Acute myeloid leukaemiaB-cell lymphomaDiabetes mellitusClinical-translation mediationFusion and delivery mediationImmune mediation70.38
TRPC6Q9Y210Short transient receptor potential channel 6 (TrpC6) (Transient receptor protein 6) (TRP-6)Disease related genesHuman disease related genesPlasma proteins6Fusion and delivery mediationImmune mediationMetabolism mediation70.38
CADM3Q8N126Cell adhesion molecule 3 (Brain immunoglobulin receptor) (Immunoglobulin superfamily member 4B) (IgSF4B) (Nectin-like protein 1) (NECL-1) (Synaptic cell adhesion molecule 3) (SynCAM3) (TSLC1-like protein 1) (TSLL1)Disease related genesHuman disease related genesPredicted intracellular proteins1Adhesion and uptake mediationReceptor-signaling mediation60.38
EPHB3P54753Ephrin type-B receptor 3 (EC 2.7.10.1) (EPH-like tyrosine kinase 2) (EPH-like kinase 2) (Embryonic kinase 2) (EK2) (hEK2) (Tyrosine-protein kinase TYRO6)Cancer-related genesEnzymesPredicted membrane proteins1Adhesion and uptake mediationReceptor-signaling mediation60.38
FCER2P06734Low affinity immunoglobulin epsilon Fc receptor (BLAST-2) (C-type lectin domain family 4 member J) (Fc-epsilon-RII) (Immunoglobulin E-binding factor) (Lymphocyte IgE receptor) (CD antigen CD23) [Cleaved into: Low affinity immunoglobulin epsilon Fc receptor membrane-bound form; Low affinity immunoglobulin epsilon Fc receptor soluble form]Cancer-related genesCD markersPredicted intracellular proteins1Adhesion and uptake mediationFusion and delivery mediationImmune mediation60.38
LRC8CQ8TDW0Volume-regulated anion channel subunit LRRC8C (Factor for adipocyte differentiation 158) (Leucine-rich repeat-containing protein 8C)Predicted membrane proteinsTransporters4Fusion and delivery mediation60.38
RHDF2Q6PJF5Inactive rhomboid protein 2 (iRhom2) (Rhomboid 5 homolog 2) (Rhomboid family member 2) (Rhomboid veinlet-like protein 5) (Rhomboid veinlet-like protein 6)Disease related genesEnzymesPotential drug targets7Skin diseaseSolid tumour/cancerClinical-translation mediationFusion and delivery mediationImmune mediation60.38
ADH1GP00326Alcohol dehydrogenase 1C (EC 1.1.1.1) (Alcohol dehydrogenase subunit gamma)EnzymesFDA approved drug targetsHuman disease related genesClinical-translation mediationMetabolism mediationReceptor-signaling mediation50.38
ARHG6Q15052Rho guanine nucleotide exchange factor 6 (Alpha-Pix) (COOL-2) (PAK-interacting exchange factor alpha) (Rac/Cdc42 guanine nucleotide exchange factor 6)Cancer-related genesPredicted intracellular proteinsReceptor-signaling mediation50.38
CD33P20138Myeloid cell surface antigen CD33 (Sialic acid-binding Ig-like lectin 3) (Siglec-3) (gp67) (CD antigen CD33)CD markersFDA approved drug targetsPlasma proteins1Acute myeloid leukaemiaAlzheimer diseaseBCR-ABL1-negative chronic myeloid leukaemiaClinical-translation mediationFusion and delivery mediationImmune mediation50.38
FLNAP21333Filamin-A (FLN-A) (Actin-binding protein 280) (ABP-280) (Alpha-filamin) (Endothelial actin-binding protein) (Filamin-1) (Non-muscle filamin)Disease related genesHuman disease related genesPlasma proteinsAlzheimer diseaseAdhesion and uptake mediationClinical-translation mediationFusion and delivery mediation50.38
KPCAP17252Protein kinase C alpha type (PKC-A) (PKC-alpha) (EC 2.7.11.13)Cancer-related genesEnzymesFDA approved drug targetsHuman immunodeficiency virus diseaseMuscular atrophyNephritic syndromeAdhesion and uptake mediationClinical-translation mediationFusion and delivery mediation50.38

426-450 of 792 proteins

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