Browse EV MemProt Atlas
Supporting publications (n)
Number of publications supporting the inclusion of this protein in EV MemProt Atlas.
EVMP confidence score
Annotation confidence score; open for threshold definitions.
Extremely high >= 0.85High >= 0.70Medium >= 0.55Low >= 0.40| UniProt ID | Protein names | Protein classification | Transmembrane count | Related Diseases | Mediation categories | Download | ||||
|---|---|---|---|---|---|---|---|---|---|---|
| SORC2 | Q96PQ0 | VPS10 domain-containing receptor SorCS2 [Cleaved into: SorCS2 122 kDa chain; SorCS2 104 kDa chain; SorCS2 18 kDa chain] | 1 | Fusion and delivery mediationReceptor-signaling mediation | 1 | 0.25 | ||||
| SORL | Q92673 | Sortilin-related receptor (Low-density lipoprotein receptor relative with 11 ligand-binding repeats) (LDLR relative with 11 ligand-binding repeats) (LR11) (SorLA-1) (Sorting protein-related receptor containing LDLR class A repeats) (SorLA) | Disease related genesPlasma proteinsPotential drug targets | 1 | Adhesion and uptake mediationFusion and delivery mediationMetabolism mediation | 1 | 0.25 | |||
| TEFF1 | Q8IYR6 | Tomoregulin-1 (TR-1) (H7365) (Transmembrane protein with EGF-like and one follistatin-like domain) | Predicted membrane proteinsTransporters | 1 | Other mediation | 1 | 0.25 | |||
| TFR1 | P02786 | Transferrin receptor protein 1 (TR) (TfR) (TfR1) (Trfr) (T9) (Transferrin receptor 1) (p90) (CD antigen CD71) [Cleaved into: Transferrin receptor protein 1, serum form (sTfR)] | Cancer-related genesCD markersDisease related genes | 1 | Diffuse large B-cell lymphomaMalignant haematopoietic neoplasmSolid tumour/cancer | Adhesion and uptake mediationClinical-translation mediationFusion and delivery mediation | 1 | 0.25 | ||
| TGBR3 | Q03167 | Transforming growth factor beta receptor type 3 (TGF-beta receptor type 3) (TGFR-3) (Betaglycan) (Transforming growth factor beta receptor III) (TGF-beta receptor type III) | Cancer-related genesPlasma proteinsPredicted membrane proteins | 1 | Fusion and delivery mediationImmune mediationReceptor-signaling mediation | 1 | 0.25 | |||
| TIGIT | Q495A1 | T-cell immunoreceptor with Ig and ITIM domains (V-set and immunoglobulin domain-containing protein 9) (V-set and transmembrane domain-containing protein 3) | 1 | Cervical cancerLung cancerNon-small-cell lung cancer | Adhesion and uptake mediationClinical-translation mediationImmune mediation | 1 | 0.25 | |||
| TLR1 | Q15399 | Toll-like receptor 1 (Toll/interleukin-1 receptor-like protein) (TIL) (CD antigen CD281) | 1 | Clinical-translation mediationFusion and delivery mediationImmune mediation | 1 | 0.25 | ||||
| TM63A | O94886 | Mechanosensitive cation channel TMEM63A (Transmembrane protein 63A) (hTMEM63A) | 11 | Fusion and delivery mediationImmune mediationMetabolism mediation | 1 | 0.25 | ||||
| TM87A | Q8NBN3 | Transmembrane protein 87A (Elkin1) | Predicted intracellular proteinsPredicted membrane proteinsTransporters | 7 | Receptor-signaling mediation | 1 | 0.25 | |||
| TMIG2 | Q96BF3 | Transmembrane and immunoglobulin domain-containing protein 2 (CD28 homolog) (Immunoglobulin and proline-rich receptor 1) (IGPR-1) | Predicted intracellular proteinsPredicted membrane proteins | 1 | Adhesion and uptake mediationImmune mediationReceptor-signaling mediation | 1 | 0.25 | |||
| TMPS5 | Q9H3S3 | Transmembrane protease serine 5 (EC 3.4.21.-) (Spinesin) | 1 | Other mediation | 1 | 0.25 | ||||
| TNF18 | Q9UNG2 | Tumor necrosis factor ligand superfamily member 18 (Activation-inducible TNF-related ligand) (AITRL) (Glucocorticoid-induced TNF-related ligand) (hGITRL) | 1 | Adhesion and uptake mediationImmune mediation | 1 | 0.25 | ||||
| TNR17 | Q02223 | Tumor necrosis factor receptor superfamily member 17 (B-cell maturation protein) (CD antigen CD269) | 1 | Follicular lymphomaLeukaemiaLymphoma | Clinical-translation mediationImmune mediation | 1 | 0.25 | |||
| TPBG | Q13641 | Trophoblast glycoprotein (5T4 oncofetal antigen) (5T4 oncofetal trophoblast glycoprotein) (5T4 oncotrophoblast glycoprotein) (M6P1) (Wnt-activated inhibitory factor 1) (WAIF1) | Predicted membrane proteins | 1 | Breast cancerLung cancerProstate cancer | Clinical-translation mediationImmune mediationReceptor-signaling mediation | 1 | 0.25 | ||
| TRFR | P34981 | Thyrotropin-releasing hormone receptor (TRH-R) (Thyroliberin receptor) | Disease related genesFDA approved drug targetsG-protein coupled receptors | 7 | Central nervous system diseaseEndocrine diseaseMild neurocognitive disorder | Clinical-translation mediationReceptor-signaling mediation | 1 | 0.25 | ||
| TSN33 | Q86UF1 | Tetraspanin-33 (Tspan-33) (Penumbra) (hPen) (Proerythroblast new membrane) | Predicted membrane proteinsTransporters | 4 | Fusion and delivery mediationMetabolism mediation | 1 | 0.25 | |||
| TTYH2 | Q9BSA4 | Protein tweety homolog 2 (hTTY2) (Volume-regulated anion channel subunit TTYH2) | 5 | Fusion and delivery mediation | 1 | 0.25 | ||||
| TYRO3 | Q06418 | Tyrosine-protein kinase receptor TYRO3 (EC 2.7.10.1) (Tyrosine-protein kinase BYK) (Tyrosine-protein kinase DTK) (Tyrosine-protein kinase RSE) (Tyrosine-protein kinase SKY) (Tyrosine-protein kinase TIF) | Cancer-related genesEnzymesPlasma proteins | 1 | Solid tumour/cancer | Adhesion and uptake mediationClinical-translation mediationImmune mediation | 1 | 0.25 | ||
| UNC5B | Q8IZJ1 | Netrin receptor UNC5B (Protein unc-5 homolog 2) (Protein unc-5 homolog B) (p53-regulated receptor for death and life protein 1) (p53RDL1) | Plasma proteinsPredicted membrane proteins | 1 | Fusion and delivery mediationReceptor-signaling mediation | 1 | 0.25 | |||
| UNC5C | O95185 | Netrin receptor UNC5C (Protein unc-5 homolog 3) (Protein unc-5 homolog C) | 1 | Other mediation | 1 | 0.25 | ||||
| VIPR1 | P32241 | Vasoactive intestinal polypeptide receptor 1 (VIP-R-1) (Pituitary adenylate cyclase-activating polypeptide type II receptor) (PACAP type II receptor) (PACAP-R-2) (PACAP-R2) (VPAC1 receptor) (VPAC1R) | G-protein coupled receptorsPredicted membrane proteinsTransporters | 7 | Chronic obstructive pulmonary diseasePulmonary hypertension | Clinical-translation mediationReceptor-signaling mediation | 1 | 0.25 | ||
| ZP4 | Q12836 | Zona pellucida sperm-binding protein 4 (Zona pellucida glycoprotein 4) (Zp-4) (Zona pellucida protein B) [Cleaved into: Processed zona pellucida sperm-binding protein 4] | Predicted membrane proteinsPredicted secreted proteins | 1 | Adhesion and uptake mediationFusion and delivery mediationImmune mediation | 1 | 0.25 | |||
| CRUM2 | Q5IJ48 | Protein crumbs homolog 2 (Crumbs-like protein 2) | Disease related genesHuman disease related genesPotential drug targets | 1 | Adhesion and uptake mediationFusion and delivery mediation | 0.25 | ||||
| ENPP1 | P22413 | Ectonucleotide pyrophosphatase/phosphodiesterase family member 1 (E-NPP 1) (Alkaline phosphodiesterase I) (EC 3.1.4.1) (Membrane component chromosome 6 surface marker 1) (Nucleotide diphosphatase) (Nucleotide pyrophosphatase) (NPPase) (EC 3.6.1.9) (Phosphodiesterase I/nucleotide pyrophosphatase 1) (Plasma-cell membrane glycoprotein PC-1) [Cleaved into: Ectonucleotide pyrophosphatase/phosphodiesterase family member 1, secreted form] | CD markersDisease related genesEnzymes | 1 | Pseudoxanthoma elasticumVitamin/non-protein cofactor absorption/transport disorder | Clinical-translation mediationFusion and delivery mediationMetabolism mediation | 0.25 | |||
| FAT1 | Q14517 | Protocadherin Fat 1 (Cadherin family member 7) (Cadherin-related tumor suppressor homolog) (Protein fat homolog) [Cleaved into: Protocadherin Fat 1, nuclear form] | Cancer-related genesPredicted intracellular proteinsPredicted membrane proteins | 1 | Adhesion and uptake mediationFusion and delivery mediation | 0.25 |