Browse EV MemProt Atlas
Supporting publications (n)

Number of publications supporting the inclusion of this protein in EV MemProt Atlas.

EVMP confidence score

Annotation confidence score; open for threshold definitions.

Extremely high >= 0.85High >= 0.70Medium >= 0.55Low >= 0.40
UniProt IDProtein namesProtein classificationTransmembrane countRelated DiseasesMediation categoriesDownload
ACESP22303Acetylcholinesterase (AChE) (EC 3.1.1.7)Alzheimer diseaseDementiaGlaucomaAdhesion and uptake mediationClinical-translation mediationFusion and delivery mediation20.25
ADA2CP18825Alpha-2C adrenergic receptor (Alpha-2 adrenergic receptor subtype C4) (Alpha-2C adrenoreceptor) (Alpha-2C adrenoceptor) (Alpha-2CAR)FDA approved drug targetsG-protein coupled receptorsPredicted membrane proteins7Acute diabete complicationAlzheimer diseaseAsthmaClinical-translation mediationFusion and delivery mediationImmune mediation20.25
ANO9A1A5B4Anoctamin-9 (Transmembrane protein 16J) (Tumor protein p53-inducible protein 5) (p53-induced gene 5 protein)Predicted membrane proteinsTransporters8Clinical-translation mediationFusion and delivery mediation20.25
APJP35414Apelin receptor (Angiotensin receptor-like 1) (G-protein coupled receptor APJ) (G-protein coupled receptor HG11)G-protein coupled receptorsPredicted membrane proteinsTransporters7Heart failureAdhesion and uptake mediationClinical-translation mediationFusion and delivery mediation20.25
AVR2AP27037Activin receptor type-2A (EC 2.7.11.30) (Activin receptor type IIA) (ACTR-IIA) (ACTRIIA)Cancer-related genesEnzymesPredicted membrane proteins1Acute myeloid leukaemiaIdiopathic inflammatory myopathyMuscle disorderClinical-translation mediationImmune mediationReceptor-signaling mediation20.25
CADM2Q8N3J6Cell adhesion molecule 2 (Immunoglobulin superfamily member 4D) (IgSF4D) (Nectin-like protein 3) (NECL-3) (Synaptic cell adhesion molecule 2) (SynCAM 2)Predicted membrane proteins1Adhesion and uptake mediationReceptor-signaling mediation20.25
CC50AQ9NV96Cell cycle control protein 50A (P4-ATPase flippase complex beta subunit TMEM30A) (Transmembrane protein 30A)Predicted intracellular proteinsPredicted membrane proteinsTransporters2Clinical-translation mediationFusion and delivery mediationImmune mediation20.25
CD244Q9BZW8Natural killer cell receptor 2B4 (NK cell activation-inducing ligand) (NAIL) (NK cell type I receptor protein 2B4) (NKR2B4) (h2B4) (SLAM family member 4) (SLAMF4) (Signaling lymphocytic activation molecule 4) (CD antigen CD244)1Fusion and delivery mediationImmune mediation20.25
CD27P26842CD27 antigen (CD27L receptor) (T-cell activation antigen CD27) (T14) (Tumor necrosis factor receptor superfamily member 7) (CD antigen CD27)Cancer-related genesCD markersDisease related genes1Brain cancerColorectal cancerHead and neck cancerAdhesion and uptake mediationClinical-translation mediationFusion and delivery mediation20.25
CD70P32970CD70 antigen (CD27 ligand) (CD27-L) (Tumor necrosis factor ligand superfamily member 7) (CD antigen CD70)1Adhesion and uptake mediationImmune mediationReceptor-signaling mediation20.25
CD79AP11912B-cell antigen receptor complex-associated protein alpha chain (Ig-alpha) (MB-1 membrane glycoprotein) (Membrane-bound immunoglobulin-associated protein) (Surface IgM-associated protein) (CD antigen CD79a)Cancer-related genesCD markersDisease related genes1Clinical-translation mediationFusion and delivery mediationImmune mediation20.25
CELR3Q9NYQ7Cadherin EGF LAG seven-pass G-type receptor 3 (Cadherin family member 11) (Epidermal growth factor-like protein 1) (EGF-like protein 1) (Flamingo homolog 1) (hFmi1) (Multiple epidermal growth factor-like domains protein 2) (Multiple EGF-like domains protein 2)G-protein coupled receptorsPlasma proteinsPredicted membrane proteins7Adhesion and uptake mediationReceptor-signaling mediation20.25
CL12AQ5QGZ9C-type lectin domain family 12 member A (C-type lectin-like molecule 1) (CLL-1) (Dendritic cell-associated lectin 2) (DCAL-2) (Killer cell C-type lectin-like receptor L1) (hKLRL1) (Myeloid inhibitory C-type lectin-like receptor) (MICL) (CD antigen CD371)CD markersPredicted intracellular proteinsPredicted membrane proteins1Fusion and delivery mediationImmune mediation20.25
CNR2P34972Cannabinoid receptor 2 (CB-2) (CB2) (hCB2) (CX5)FDA approved drug targetsG-protein coupled receptorsPredicted membrane proteins7Clinical-translation mediationImmune mediationReceptor-signaling mediation20.25
CXL16Q9H2A7C-X-C motif chemokine 16 (Scavenger receptor for phosphatidylserine and oxidized low density lipoprotein) (SR-PSOX) (Small-inducible cytokine B16) (Transmembrane chemokine CXCL16)Predicted intracellular proteinsPredicted membrane proteinsPredicted secreted proteins1Adhesion and uptake mediationImmune mediationReceptor-signaling mediation20.25
CY24BP04839NADPH oxidase 2 (EC 1.6.3.-) (CGD91-phox) (Cytochrome b(558) subunit beta) (Cytochrome b558 subunit beta) (Cytochrome b-245 heavy chain) (Heme-binding membrane glycoprotein gp91phox) (Neutrophil cytochrome b 91 kDa polypeptide) (Superoxide-generating NADPH oxidase heavy chain subunit) (gp91-1) (gp91-phox) (p22 phagocyte B-cytochrome)Disease related genesHuman disease related genesPotential drug targets6Fusion and delivery mediationImmune mediationMetabolism mediation20.25
DRAP01903HLA class II histocompatibility antigen, DR alpha chain (MHC class II antigen DRA)Plasma proteinsPredicted membrane proteins1Adhesion and uptake mediationFusion and delivery mediationImmune mediation20.25
EFNA5P52803Ephrin-A5 (AL-1) (EPH-related receptor tyrosine kinase ligand 7) (LERK-7)Cancer-related genesPredicted membrane proteinsRAS pathway related proteinsAdhesion and uptake mediationFusion and delivery mediationMetabolism mediation20.25
EMP2P54851Epithelial membrane protein 2 (EMP-2) (Protein XMP)Disease related genesHuman disease related genesPredicted membrane proteins4Adhesion and uptake mediationFusion and delivery mediationImmune mediation20.25
EPHB4P54760Ephrin type-B receptor 4 (EC 2.7.10.1) (Hepatoma transmembrane kinase) (Tyrosine-protein kinase TYRO11)Cancer-related genesDisease related genesEnzymes1Brain cancerCystic/dysplastic kidney diseaseLung cancerClinical-translation mediationReceptor-signaling mediation20.25
FCRLBQ6BAA4Fc receptor-like B (Fc receptor homolog expressed in B-cells protein 2) (FREB-2) (Fc receptor-like and mucin-like protein 2) (Fc receptor-like protein 2) (Fc receptor-related protein Y) (FcRY)Fusion and delivery mediation20.25
FOLR1P15328Folate receptor alpha (FR-alpha) (Adult folate-binding protein) (FBP) (Folate receptor 1) (Folate receptor, adult) (KB cells FBP) (Ovarian tumor-associated antigen MOv18)Endometrial cancerLung cancerMalariaAdhesion and uptake mediationClinical-translation mediationFusion and delivery mediation20.25
GBRB3P28472Gamma-aminobutyric acid receptor subunit beta-3 (GABA(A) receptor subunit beta-3) (GABAAR subunit beta-3)4Fusion and delivery mediationReceptor-signaling mediation20.25
GP176Q14439G-protein coupled receptor 176 (HB-954)G-protein coupled receptorsPredicted membrane proteins7Receptor-signaling mediation20.25
GRIK3Q13003Glutamate receptor ionotropic, kainate 3 (GluK3) (Excitatory amino acid receptor 5) (EAA5) (Glutamate receptor 7) (GluR-7) (GluR7)3Fusion and delivery mediationReceptor-signaling mediation20.25

1,926-1,950 of 2,176 proteins

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