Browse EV MemProt Atlas
Supporting publications (n)

Number of publications supporting the inclusion of this protein in EV MemProt Atlas.

EVMP confidence score

Annotation confidence score; open for threshold definitions.

Extremely high >= 0.85High >= 0.70Medium >= 0.55Low >= 0.40
UniProt IDProtein namesProtein classificationTransmembrane countRelated DiseasesMediation categoriesDownload
ANK2Q01484Ankyrin-2 (ANK-2) (Ankyrin-B) (Brain ankyrin) (Non-erythroid ankyrin)Disease related genesHuman disease related genesPlasma proteinsFusion and delivery mediationImmune mediationMetabolism mediation10.50
ANKL2Q86XL3Ankyrin repeat and LEM domain-containing protein 2 (LEM domain-containing protein 4)Disease related genesEssential proteinsHuman disease related genes1Receptor-signaling mediation10.50
ANO1Q5XXA6Anoctamin-1 (Discovered on gastrointestinal stromal tumors protein 1) (Oral cancer overexpressed protein 2) (Transmembrane protein 16A) (Tumor-amplified and overexpressed sequence 2)Disease related genesFDA approved drug targetsPlasma proteins10Clinical-translation mediationFusion and delivery mediationMetabolism mediation10.50
APCP25054Adenomatous polyposis coli protein (Protein APC) (Deleted in polyposis 2.5)Cancer-related genesDisease related genesHuman disease related genesClinical-translation mediationFusion and delivery mediationMetabolism mediation10.50
AQP4P55087Aquaporin-4 (AQP-4) (Mercurial-insensitive water channel) (MIWC) (WCH4)Human disease related genesMetabolic proteinsPredicted membrane proteins6Fusion and delivery mediationMetabolism mediation10.50
AT1A1P05023Sodium/potassium-transporting ATPase subunit alpha-1 (Na(+)/K(+) ATPase alpha-1 subunit) (EC 7.2.2.13) (Sodium pump subunit alpha-1)Cancer-related genesDisease related genesEnzymes10Cardiac arrhythmiaChronic obstructive pulmonary diseaseCorneal diseaseClinical-translation mediationFusion and delivery mediation10.50
AT2A2P16615Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 (SERCA2) (SR Ca(2+)-ATPase 2) (EC 7.2.2.10) (Calcium pump 2) (Calcium-transporting ATPase sarcoplasmic reticulum type, slow twitch skeletal muscle isoform) (Endoplasmic reticulum class 1/2 Ca(2+) ATPase)Disease related genesEnzymesEssential proteins10AsthmaHeart failureHypertensionClinical-translation mediationFusion and delivery mediationImmune mediation10.50
AT2B1P20020Plasma membrane calcium-transporting ATPase 1 (EC 7.2.2.10) (Plasma membrane calcium ATPase isoform 1) (PMCA1) (Plasma membrane calcium pump isoform 1)Disease related genesEnzymesFDA approved drug targets10Clinical-translation mediationFusion and delivery mediationImmune mediation10.50
AT2B3Q16720Plasma membrane calcium-transporting ATPase 3 (PMCA3) (EC 7.2.2.10) (Plasma membrane calcium ATPase isoform 3) (Plasma membrane calcium pump isoform 3)Cancer-related genesDisease related genesEnzymes10Clinical-translation mediationFusion and delivery mediationImmune mediation10.50
AT2C2O75185Calcium-transporting ATPase type 2C member 2 (ATPase 2C2) (EC 7.2.2.10) (Ca(2+)/Mn(2+)-ATPase 2C2) (Secretory pathway Ca(2+)-transporting ATPase type 2) (SPCA2)EnzymesFDA approved drug targetsMetabolic proteins10Clinical-translation mediationFusion and delivery mediationMetabolism mediation10.50
AT8A2Q9NTI2Phospholipid-transporting ATPase IB (EC 7.6.2.1) (ATPase class I type 8A member 2) (ML-1) (P4-ATPase flippase complex alpha subunit ATP8A2)Disease related genesEnzymesHuman disease related genes10Fusion and delivery mediation10.50
AT8B1O43520Phospholipid-transporting ATPase IC (EC 7.6.2.1) (ATPase class I type 8B member 1) (Familial intrahepatic cholestasis type 1) (P4-ATPase flippase complex alpha subunit ATP8B1)Disease related genesEnzymesHuman disease related genes10Clinical-translation mediationFusion and delivery mediation10.50
BFSP1Q12934Filensin (Beaded filament structural protein 1) (Lens fiber cell beaded-filament structural protein CP 115) (CP115) (Lens intermediate filament-like heavy) (LIFL-H) [Cleaved into: Filensin C-terminal fragment; Filensin N-terminal fragment]Disease related genesHuman disease related genesPredicted intracellular proteinsFusion and delivery mediation10.50
BFSP2Q13515Phakinin (49 kDa cytoskeletal protein) (Beaded filament structural protein 2) (Lens fiber cell beaded filament protein CP 47) (CP47) (Lens fiber cell beaded filament protein CP 49) (CP49) (Lens intermediate filament-like light) (LIFL-L)Disease related genesHuman disease related genesPredicted intracellular proteinsFusion and delivery mediation10.50
BMPR2Q13873Bone morphogenetic protein receptor type-2 (BMP type-2 receptor) (BMPR-2) (EC 2.7.11.30) (Bone morphogenetic protein receptor type II) (BMP type II receptor) (BMPR-II)Disease related genesEnzymesFDA approved drug targets1Joint derangementProstate cancerUrinary system diseaseClinical-translation mediationFusion and delivery mediationImmune mediation10.50
C1QBPQ07021Complement component 1 Q subcomponent-binding protein, mitochondrial (ASF/SF2-associated protein p32) (Glycoprotein gC1qBP) (C1qBP) (Hyaluronan-binding protein 1) (Mitochondrial matrix protein p32) (gC1q-R protein) (p33) (SF2AP32)Cancer-related genesDisease related genesHuman disease related genesAdhesion and uptake mediationClinical-translation mediationImmune mediation10.50
CAC1CQ13936Voltage-dependent L-type calcium channel subunit alpha-1C (Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle) (Voltage-gated calcium channel subunit alpha Cav1.2)Disease related genesFDA approved drug targetsHuman disease related genes24Alzheimer diseaseAngina pectorisGenetic cardiac arrhythmiaClinical-translation mediationFusion and delivery mediationMetabolism mediation10.50
CADH1P12830Cadherin-1 (CAM 120/80) (Epithelial cadherin) (E-cadherin) (Uvomorulin) (CD antigen CD324) [Cleaved into: E-Cad/CTF1; E-Cad/CTF2; E-Cad/CTF3]Cancer-related genesCD markersDisease related genes1Adhesion and uptake mediationClinical-translation mediationFusion and delivery mediation10.50
CADH2P19022Cadherin-2 (CDw325) (Neural cadherin) (N-cadherin) (CD antigen CD325)CD markersDisease related genesHuman disease related genes1Solid tumour/cancerAdhesion and uptake mediationClinical-translation mediationFusion and delivery mediation10.50
CADH3P22223Cadherin-3 (Placental cadherin) (P-cadherin)Disease related genesHuman disease related genesPredicted intracellular proteins1Solid tumour/cancerAdhesion and uptake mediationClinical-translation mediationFusion and delivery mediation10.50
CANB1P63098Calcineurin subunit B type 1 (Protein phosphatase 2B regulatory subunit 1) (Protein phosphatase 3 regulatory subunit B alpha isoform 1)FDA approved drug targetsPredicted intracellular proteinsAdhesion and uptake mediationClinical-translation mediationFusion and delivery mediation10.50
CAV3P56539Caveolin-3 (M-caveolin)Disease related genesHuman disease related genesPotential drug targetsAdhesion and uptake mediationFusion and delivery mediationMetabolism mediation10.50
CAVN1Q6NZI2Caveolae-associated protein 1 (Cavin-1) (Polymerase I and transcript release factor)Disease related genesHuman disease related genesPlasma proteinsFusion and delivery mediationReceptor-signaling mediation10.50
CD2P06729T-cell surface antigen CD2 (Erythrocyte receptor) (LFA-2) (LFA-3 receptor) (Rosette receptor) (T-cell surface antigen T11/Leu-5) (CD antigen CD2)CD markersFDA approved drug targetsPredicted intracellular proteins1LymphomaPsoriasisClinical-translation mediationFusion and delivery mediationImmune mediation10.50
CD20P11836B-lymphocyte antigen CD20 (B-lymphocyte surface antigen B1) (Bp35) (Leukocyte surface antigen Leu-16) (Membrane-spanning 4-domains subfamily A member 1) (CD antigen CD20)CD markersDisease related genesFDA approved drug targets4Clinical-translation mediationFusion and delivery mediationImmune mediation10.50

251-275 of 792 proteins

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