Browse EV MemProt Atlas
Supporting publications (n)
Number of publications supporting the inclusion of this protein in EV MemProt Atlas.
EVMP confidence score
Annotation confidence score; open for threshold definitions.
Extremely high >= 0.85High >= 0.70Medium >= 0.55Low >= 0.40| UniProt ID | Protein names | Protein classification | Transmembrane count | Related Diseases | Mediation categories | Download | ||||
|---|---|---|---|---|---|---|---|---|---|---|
| MSLN | Q13421 | Mesothelin (CAK1 antigen) (Pre-pro-megakaryocyte-potentiating factor) [Cleaved into: Megakaryocyte-potentiating factor (MPF); Mesothelin, cleaved form] | Cancer-related genesDisease related genesPlasma proteins | Breast cancerCervical cancerEndometrial cancer | Adhesion and uptake mediationClinical-translation mediationMetabolism mediation | 5 | 0.38 | |||
| SL9A6 | Q92581 | Sodium/hydrogen exchanger 6 (Na(+)/H(+) exchanger 6) (NHE-6) (Solute carrier family 9 member 6) | Disease related genesHuman disease related genesPotential drug targets | 12 | Clinical-translation mediationFusion and delivery mediation | 5 | 0.38 | |||
| TNR5 | P25942 | Tumor necrosis factor receptor superfamily member 5 (B-cell surface antigen CD40) (Bp50) (CD40L receptor) (CDw40) (CD antigen CD40) | Cancer-related genesCD markersDisease related genes | 1 | Brain cancerCrohn diseaseDiabetes mellitus | Clinical-translation mediationFusion and delivery mediationImmune mediation | 5 | 0.38 | ||
| ACM4 | P08173 | Muscarinic acetylcholine receptor M4 | FDA approved drug targetsG-protein coupled receptorsPredicted membrane proteins | 7 | AsthmaAttention deficit hyperactivity disorderEye anterior segment structural developmental anomaly | Clinical-translation mediationReceptor-signaling mediation | 4 | 0.38 | ||
| CCD62 | Q6P9F0 | Coiled-coil domain-containing protein 62 (Protein TSP-NY) (Protein aaa) | Disease related genesHuman disease related genesPredicted intracellular proteins | Other mediation | 4 | 0.38 | ||||
| CEAM5 | P06731 | Cell adhesion molecule CEACAM5 (Carcinoembryonic antigen) (CEA) (Carcinoembryonic antigen-related cell adhesion molecule 5) (CEA cell adhesion molecule 5) (Meconium antigen 100) (CD antigen CD66e) | Cancer-related genesCD markersPlasma proteins | Adhesion and uptake mediationFusion and delivery mediationImmune mediation | 4 | 0.38 | ||||
| CRTC1 | Q6UUV9 | CREB-regulated transcription coactivator 1 (Mucoepidermoid carcinoma translocated protein 1) (Transducer of regulated cAMP response element-binding protein 1) (TORC-1) (Transducer of CREB protein 1) | Cancer-related genesDisease related genesHuman disease related genes | Other mediation | 4 | 0.38 | ||||
| DDX3X | O00571 | ATP-dependent RNA helicase DDX3X (EC 3.6.4.13) (CAP-Rf) (DEAD box protein 3, X-chromosomal) (DEAD box, X isoform) (DBX) (Helicase-like protein 2) (HLP2) | Cancer-related genesDisease related genesEnzymes | Clinical-translation mediationImmune mediationReceptor-signaling mediation | 4 | 0.38 | ||||
| DRC4 | O95995 | Dynein regulatory complex subunit 4 (Growth arrest-specific protein 11) (GAS-11) (Growth arrest-specific protein 8) (GAS-8) | Disease related genesHuman disease related genesPlasma proteins | Receptor-signaling mediation | 4 | 0.38 | ||||
| ENOA | P06733 | Alpha-enolase (EC 4.2.1.11) (2-phospho-D-glycerate hydro-lyase) (C-myc promoter-binding protein) (Enolase 1) (MBP-1) (MPB-1) (Non-neural enolase) (NNE) (Phosphopyruvate hydratase) (Plasminogen-binding protein) | Cancer-related genesEnzymesMetabolic proteins | Clinical-translation mediationFusion and delivery mediationMetabolism mediation | 4 | 0.38 | ||||
| F16P2 | O00757 | Fructose-1,6-bisphosphatase isozyme 2 (FBPase 2) (EC 3.1.3.11) (D-fructose-1,6-bisphosphate 1-phosphohydrolase 2) (Muscle FBPase) | Disease related genesEnzymesMetabolic proteins | Metabolism mediation | 4 | 0.38 | ||||
| GAB1 | Q13480 | GRB2-associated-binding protein 1 (GRB2-associated binder 1) (Growth factor receptor bound protein 2-associated protein 1) | Disease related genesHuman disease related genesPredicted intracellular proteins | Clinical-translation mediationImmune mediationReceptor-signaling mediation | 4 | 0.38 | ||||
| GLNA | P15104 | Glutamine synthetase (GS) (EC 6.3.1.2) (Glutamate--ammonia ligase) (Palmitoyltransferase GLUL) (EC 2.3.1.225) | Disease related genesEnzymesHuman disease related genes | Parkinsonism | Clinical-translation mediationMetabolism mediationReceptor-signaling mediation | 4 | 0.38 | |||
| HCK | P08631 | Tyrosine-protein kinase HCK (EC 2.7.10.2) (Hematopoietic cell kinase) (Hemopoietic cell kinase) (p59-HCK/p60-HCK) (p59Hck) (p61Hck) | Disease related genesEnzymesPotential drug targets | Indeterminate colitis | Adhesion and uptake mediationClinical-translation mediationFusion and delivery mediation | 4 | 0.38 | |||
| HPS4 | Q9NQG7 | BLOC-3 complex member HPS4 (Hermansky-Pudlak syndrome 4 protein) (Light-ear protein homolog) | Disease related genesHuman disease related genesPredicted intracellular proteins | Fusion and delivery mediationImmune mediation | 4 | 0.38 | ||||
| MYO5B | Q9ULV0 | Unconventional myosin-Vb | Disease related genesHuman disease related genesMetabolic proteins | Fusion and delivery mediationMetabolism mediation | 4 | 0.38 | ||||
| PHAR1 | Q9C0D0 | Phosphatase and actin regulator 1 | Disease related genesHuman disease related genesPredicted intracellular proteins | Fusion and delivery mediation | 4 | 0.38 | ||||
| RHBT2 | Q9BYZ6 | Rho-related BTB domain-containing protein 2 (Deleted in breast cancer 2 gene protein) (p83) | Disease related genesHuman disease related genesPredicted intracellular proteins | Fusion and delivery mediationReceptor-signaling mediation | 4 | 0.38 | ||||
| RPIA | P49247 | Ribose-5-phosphate isomerase (EC 5.3.1.6) (Phosphoriboisomerase) | Disease related genesEnzymesHuman disease related genes | Clinical-translation mediationMetabolism mediation | 4 | 0.38 | ||||
| SEPT2 | Q15019 | Septin-2 (Neural precursor cell expressed developmentally down-regulated protein 5) (NEDD-5) | Cancer-related genesPlasma proteinsPredicted intracellular proteins | Fusion and delivery mediation | 4 | 0.38 | ||||
| ADCY3 | O60266 | Adenylate cyclase type 3 (EC 4.6.1.1) (ATP pyrophosphate-lyase 3) (Adenylate cyclase type III) (AC-III) (Adenylate cyclase, olfactive type) (Adenylyl cyclase 3) (AC3) | Disease related genesEnzymesHuman disease related genes | 12 | Clinical-translation mediationFusion and delivery mediationMetabolism mediation | 3 | 0.38 | |||
| ADH1A | P07327 | Alcohol dehydrogenase 1A (EC 1.1.1.1) (Alcohol dehydrogenase subunit alpha) | EnzymesFDA approved drug targetsMetabolic proteins | Eexposure to noxious substances harmful effect | Clinical-translation mediationMetabolism mediationReceptor-signaling mediation | 3 | 0.38 | |||
| AUXI | O75061 | Auxilin (EC 3.1.3.-) (DnaJ homolog subfamily C member 6) | Disease related genesEnzymesHuman disease related genes | Adhesion and uptake mediationFusion and delivery mediation | 3 | 0.38 | ||||
| BANK1 | Q8NDB2 | B-cell scaffold protein with ankyrin repeats | Disease related genesHuman disease related genesPredicted intracellular proteins | Immune mediationReceptor-signaling mediation | 3 | 0.38 | ||||
| COF2 | Q9Y281 | Cofilin-2 (Cofilin, muscle isoform) | Disease related genesHuman disease related genesPlasma proteins | Fusion and delivery mediation | 3 | 0.38 |