Browse EV MemProt Atlas
Supporting publications (n)

Number of publications supporting the inclusion of this protein in EV MemProt Atlas.

EVMP confidence score

Annotation confidence score; open for threshold definitions.

Extremely high >= 0.85High >= 0.70Medium >= 0.55Low >= 0.40
UniProt IDProtein namesProtein classificationTransmembrane countRelated DiseasesMediation categoriesDownload
PLVAPQ9BX97Plasmalemma vesicle-associated protein (Fenestrated endothelial-linked structure protein) (Plasmalemma vesicle protein 1) (PV-1)Disease related genesHuman disease related genesPlasma proteins1Fusion and delivery mediationImmune mediationReceptor-signaling mediation80.50
SASH3O75995SAM and SH3 domain-containing protein 3 (SH3 protein expressed in lymphocytes homolog)Disease related genesPredicted intracellular proteinsAdhesion and uptake mediationImmune mediation80.50
TN13BQ9Y275Tumor necrosis factor ligand superfamily member 13B (B lymphocyte stimulator) (BLyS) (B-cell-activating factor) (BAFF) (Dendritic cell-derived TNF-like molecule) (TNF- and APOL-related leukocyte expressed ligand 1) (TALL-1) (CD antigen CD257) [Cleaved into: Tumor necrosis factor ligand superfamily member 13b, membrane form; Tumor necrosis factor ligand superfamily member 13b, soluble form]Cancer-related genesCD markersFDA approved drug targets1Lupus erythematosusLymphomaMultiple myelomaAdhesion and uptake mediationClinical-translation mediationImmune mediation80.50
ANK3Q12955Ankyrin-3 (ANK-3) (Ankyrin-G)Cancer-related genesDisease related genesHuman disease related genesAdhesion and uptake mediationFusion and delivery mediationMetabolism mediation70.50
APODP05090Apolipoprotein D (Apo-D) (ApoD)Cancer-related genesCandidate cardiovascular disease genesPlasma proteinsAdhesion and uptake mediationFusion and delivery mediationImmune mediation70.50
EI2BBP49770Translation initiation factor eIF2B subunit beta (S20I15) (S20III15) (eIF2B GDP-GTP exchange factor subunit beta)Disease related genesEssential proteinsHuman disease related genesImmune mediationMetabolism mediation70.50
FAD1Q8NFF5Bifunctional FAD diphosphatase/FAD synthase [Includes: FAD diphosphatase (EC 3.6.1.18) (EC 3.6.1.22) (FAD pyrophosphatase) (FADPPase) (FADHy) (NADH diphosphatase); FAD synthase (FADSy) (EC 2.7.7.2) (FMN adenylyltransferase) (FMNAT) (Flavin adenine dinucleotide synthase)]Disease related genesEnzymesHuman disease related genesMetabolism mediation70.50
BICD2Q8TD16Protein bicaudal D homolog 2 (Bic-D 2)Disease related genesHuman disease related genesPredicted intracellular proteinsFusion and delivery mediation60.50
CNNM4Q6P4Q7Metal transporter CNNM4 (Ancient conserved domain-containing protein 4) (Cyclin-M4)Disease related genesHuman disease related genesPotential drug targets3Fusion and delivery mediationMetabolism mediation60.50
FBW1BQ9UKB1F-box/WD repeat-containing protein 11 (F-box and WD repeats protein beta-TrCP2) (F-box/WD repeat-containing protein 1B) (Homologous to Slimb protein) (HOS)Disease related genesHuman disease related genesPlasma proteinsImmune mediationMetabolism mediationReceptor-signaling mediation60.50
FBX38Q6PIJ6F-box only protein 38Disease related genesHuman disease related genesPredicted intracellular proteinsAdhesion and uptake mediationImmune mediation60.50
LITAFQ99732Lipopolysaccharide-induced tumor necrosis factor-alpha factor (LPS-induced TNF-alpha factor) (Small integral membrane protein of lysosome/late endosome) (p53-induced gene 7 protein)Disease related genesHuman disease related genesPredicted intracellular proteinsFusion and delivery mediationImmune mediationReceptor-signaling mediation60.50
TUBP50607Tubby protein homologDisease related genesPredicted intracellular proteinsBladder cancerBrain cancerBreast cancerClinical-translation mediationImmune mediationReceptor-signaling mediation60.50
ANXA2P07355Annexin A2 (Annexin II) (Annexin-2) (Calpactin I heavy chain) (Calpactin-1 heavy chain) (Chromobindin-8) (Lipocortin II) (Placental anticoagulant protein IV) (PAP-IV) (Protein I) (p36)Cancer-related genesDisease related genesFDA approved drug targetsAdhesion and uptake mediationClinical-translation mediationFusion and delivery mediation50.50
CD4P01730T-cell surface glycoprotein CD4 (T-cell surface antigen T4/Leu-3) (CD antigen CD4)CD markersDisease related genesFDA approved drug targets1Acute myeloid leukaemiaAsthmaHuman immunodeficiency virus diseaseAdhesion and uptake mediationClinical-translation mediationFusion and delivery mediation50.50
CD86P42081T-lymphocyte activation antigen CD86 (Activation B7-2 antigen) (B70) (BU63) (CTLA-4 counter-receptor B7.2) (FUN-1) (CD antigen CD86)CD markersFDA approved drug targetsPredicted intracellular proteins1Adhesion and uptake mediationClinical-translation mediationFusion and delivery mediation50.50
COG3Q96JB2Conserved oligomeric Golgi complex subunit 3 (COG complex subunit 3) (Component of oligomeric Golgi complex 3) (Vesicle-docking protein SEC34 homolog) (p94)Essential proteinsPredicted intracellular proteinsFusion and delivery mediationMetabolism mediation50.50
DYSFO75923Dysferlin (Dystrophy-associated fer-1-like protein) (Fer-1-like protein 1)Disease related genesHuman disease related genesPotential drug targets1Muscular dystrophyClinical-translation mediationFusion and delivery mediationImmune mediation50.50
FZD6O60353Frizzled-6 (Fz-6) (hFz6)Disease related genesG-protein coupled receptorsHuman disease related genes7Clinical-translation mediationFusion and delivery mediationImmune mediation50.50
KCJ15Q99712ATP-sensitive inward rectifier potassium channel 15 (Inward rectifier K(+) channel Kir1.3) (Inward rectifier K(+) channel Kir4.2) (Potassium channel, inwardly rectifying subfamily J member 15)FDA approved drug targetsPredicted intracellular proteinsPredicted membrane proteins2Clinical-translation mediationFusion and delivery mediation50.50
KCNN3Q9UGI6Small conductance calcium-activated potassium channel protein 3 (SK3) (SKCa 3) (SKCa3) (KCa2.3)Disease related genesFDA approved drug targetsHuman disease related genes6MyelopathyClinical-translation mediationFusion and delivery mediation50.50
KPTNQ9Y664KICSTOR complex protein kaptin (Actin-associated protein 2E4)Disease related genesHuman disease related genesPredicted intracellular proteinsFusion and delivery mediation50.50
NKG2DP26718NKG2-D type II integral membrane protein (Killer cell lectin-like receptor subfamily K member 1) (NK cell receptor D) (NKG2-D-activating NK receptor) (CD antigen CD314)Cancer-related genesCD markersPredicted membrane proteins1Acute myeloid leukaemiaColorectal cancerCrohn diseaseAdhesion and uptake mediationClinical-translation mediationFusion and delivery mediation50.50
PK3CGP48736Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (PI3-kinase subunit gamma) (PI3K-gamma) (PI3Kgamma) (PtdIns-3-kinase subunit gamma) (EC 2.7.1.137) (EC 2.7.1.153) (EC 2.7.1.154) (Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit gamma) (PtdIns-3-kinase subunit p110-gamma) (p110gamma) (Phosphoinositide-3-kinase catalytic gamma polypeptide) (Serine/threonine protein kinase PIK3CG) (EC 2.7.11.1) (p120-PI3K)Cancer-related genesDisease related genesEnzymesCOVID-19Follicular lymphomaAdrenal cancerClinical-translation mediationFusion and delivery mediationImmune mediation50.50
PRRT2Q7Z6L0Proline-rich transmembrane protein 2 (Dispanin subfamily B member 3) (DSPB3)Disease related genesHuman disease related genesPotential drug targets1Fusion and delivery mediationReceptor-signaling mediation50.50