Browse EV MemProt Atlas
Supporting publications (n)

Number of publications supporting the inclusion of this protein in EV MemProt Atlas.

EVMP confidence score

Annotation confidence score; open for threshold definitions.

Extremely high >= 0.85High >= 0.70Medium >= 0.55Low >= 0.40
UniProt IDProtein namesProtein classificationTransmembrane countRelated DiseasesMediation categoriesDownload
PDPNQ86YL7Podoplanin (Aggrus) (Glycoprotein 36) (Gp36) (PA2.26 antigen) (T1-alpha) (T1A) [Cleaved into: 29kDa cytosolic podoplanin intracellular domain (PICD)]Predicted membrane proteinsTransporters1Adhesion and uptake mediationFusion and delivery mediationImmune mediation10.38
PEXRPQ6IAN0Peroxisomal reductase activating PPAR-gamma (PexRAP) (EC 1.1.1.101) (Dehydrogenase/reductase SDR family member 7B) (Short-chain dehydrogenase/reductase family 32C member 1) (Protein SDR32C1)Predicted intracellular proteinsPredicted membrane proteins1Immune mediationMetabolism mediation10.38
PTPRKQ15262Receptor-type tyrosine-protein phosphatase kappa (Protein-tyrosine phosphatase kappa) (R-PTP-kappa) (EC 3.1.3.48)Cancer-related genesEnzymesPlasma proteins1Adhesion and uptake mediationFusion and delivery mediationMetabolism mediation10.38
PTPRRQ15256Receptor-type tyrosine-protein phosphatase R (R-PTP-R) (EC 3.1.3.48) (Ch-1PTPase) (NC-PTPCOM1) (Protein-tyrosine phosphatase PCPTP1)EnzymesPlasma proteinsPredicted intracellular proteins1Metabolism mediationReceptor-signaling mediation10.38
PVRP15151Poliovirus receptor (Nectin-like protein 5) (NECL-5) (CD antigen CD155)CD markersPlasma proteinsPredicted intracellular proteins1Adhesion and uptake mediationFusion and delivery mediationImmune mediation10.38
RAI3Q8NFJ5Retinoic acid-induced protein 3 (G-protein coupled receptor family C group 5 member A) (Phorbol ester induced gene 1) (PEIG-1) (Retinoic acid-induced gene 1 protein) (RAIG-1)G-protein coupled receptorsPredicted intracellular proteinsPredicted membrane proteins7Receptor-signaling mediation10.38
RETP07949Proto-oncogene tyrosine-protein kinase receptor Ret (EC 2.7.10.1) (Cadherin family member 12) (Proto-oncogene c-Ret) [Cleaved into: Soluble RET kinase fragment; Extracellular cell-membrane anchored RET cadherin 120 kDa fragment]Cancer-related genesDisease related genesEnzymes1Breast cancerColon cancerColorectal cancerAdhesion and uptake mediationClinical-translation mediationFusion and delivery mediation10.38
S38A6Q8IZM9Solute carrier family 38 member 6 (Amino acid transporter SLC38A6) (N-system amino acid transporter 1) (NAT-1)Predicted intracellular proteinsPredicted membrane proteinsTransporters11Fusion and delivery mediation10.38
S39A6Q13433Zinc transporter ZIP6 (Estrogen-regulated protein LIV-1) (Solute carrier family 39 member 6) (Zrt- and Irt-like protein 6) (ZIP-6)Metabolic proteinsPredicted membrane proteinsTransporters6Breast cancerLung cancerNon-small-cell lung cancerClinical-translation mediationFusion and delivery mediationImmune mediation10.38
SEM6DQ8NFY4Semaphorin-6D1Immune mediationReceptor-signaling mediation10.38
SIG10Q96LC7Sialic acid-binding Ig-like lectin 10 (Siglec-10) (Siglec-like protein 2)Predicted intracellular proteinsPredicted membrane proteins1Immune mediation10.38
SIG14Q08ET2Sialic acid-binding Ig-like lectin 14 (Siglec-14)Plasma proteinsPredicted membrane proteins1Fusion and delivery mediationImmune mediation10.38
SIGL6O43699Sialic acid-binding Ig-like lectin 6 (Siglec-6) (CD33 antigen-like 1) (CDw327) (Obesity-binding protein 1) (OB-BP1) (CD antigen CD327)CD markersPredicted membrane proteinsPredicted secreted proteins1Immune mediation10.38
SORTQ99523Sortilin (100 kDa NT receptor) (Glycoprotein 95) (Gp95) (Neurotensin receptor 3) (NT3) (NTR3)Disease related genesPotential drug targetsPredicted intracellular proteins1Frontotemporal dementiaMotor neuron diseaseNeurodegenerative disorderClinical-translation mediationFusion and delivery mediationReceptor-signaling mediation10.38
STAB1Q9NY15Stabilin-1 (Fasciclin, EGF-like, laminin-type EGF-like and link domain-containing scavenger receptor 1) (FEEL-1) (MS-1 antigen)Predicted membrane proteinsTransporters1Adhesion and uptake mediationFusion and delivery mediation10.38
TRPM1Q7Z4N2Transient receptor potential cation channel subfamily M member 1 (Long transient receptor potential channel 1) (LTrpC1) (Melastatin-1)Disease related genesHuman disease related genesPotential drug targets6Fusion and delivery mediationReceptor-signaling mediation10.38
VGFR3P35916Vascular endothelial growth factor receptor 3 (VEGFR-3) (EC 2.7.10.1) (Fms-like tyrosine kinase 4) (FLT-4) (Tyrosine-protein kinase receptor FLT4)Cancer-related genesDisease related genesEnzymes1Clinical-translation mediationImmune mediationReceptor-signaling mediation10.38
VSIG4Q9Y279V-set and immunoglobulin domain-containing protein 4 (Protein Z39Ig)Plasma proteinsPredicted membrane proteins1Adhesion and uptake mediationImmune mediation10.38
X3CL1P78423Fractalkine (C-X3-C motif chemokine 1) (CX3C membrane-anchored chemokine) (Neurotactin) (Small-inducible cytokine D1) [Cleaved into: Processed fractalkine]Plasma proteinsPredicted membrane proteinsPredicted secreted proteins1Adhesion and uptake mediationFusion and delivery mediationImmune mediation10.38
YLAT2Q92536Y+L amino acid transporter 2 (Cationic amino acid transporter, y+ system) (Solute carrier family 7 member 6) (y(+)L-type amino acid transporter 2) (Y+LAT2) (y+LAT-2)Metabolic proteinsPredicted intracellular proteinsPredicted membrane proteins12Fusion and delivery mediationImmune mediation10.38
ACE2Q9BYF1Angiotensin-converting enzyme 2 (EC 3.4.17.23) (Angiotensin-converting enzyme homolog) (ACEH) (Angiotensin-converting enzyme-related carboxypeptidase) (ACE-related carboxypeptidase) (EC 3.4.17.-) (Metalloprotease MPROT15) [Cleaved into: Processed angiotensin-converting enzyme 2]EnzymesMetabolic proteinsPredicted membrane proteins1Acute diabete complicationIntrathoracic organs injuryPulmonary hypertensionAdhesion and uptake mediationClinical-translation mediationFusion and delivery mediation0.38
AGRE1Q14246Adhesion G protein-coupled receptor E1 (EGF-like module receptor 1) (EGF-like module-containing mucin-like hormone receptor-like 1) (EMR1 hormone receptor)G-protein coupled receptorsPredicted intracellular proteinsPredicted membrane proteins7Fusion and delivery mediationReceptor-signaling mediation0.38
AQP2P41181Aquaporin-2 (AQP-2) (ADH water channel) (Aquaporin-CD) (AQP-CD) (Collecting duct water channel protein) (WCH-CD) (Water channel protein for renal collecting duct)Disease related genesHuman disease related genesMetabolic proteins6Fusion and delivery mediationMetabolism mediation0.38
AT1A2P50993Sodium/potassium-transporting ATPase subunit alpha-2 (Na(+)/K(+) ATPase alpha-2 subunit) (EC 7.2.2.13) (Sodium pump subunit alpha-2)Disease related genesEnzymesHuman disease related genes10Clinical-translation mediationFusion and delivery mediationMetabolism mediation0.38
AT2B2Q01814Plasma membrane calcium-transporting ATPase 2 (PMCA2) (EC 7.2.2.10) (Plasma membrane calcium ATPase isoform 2) (Plasma membrane calcium pump isoform 2)Disease related genesEnzymesFDA approved drug targets10Clinical-translation mediationFusion and delivery mediationImmune mediation0.38

826-850 of 1,200 proteins

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