Browse EV MemProt Atlas
Supporting publications (n)

Number of publications supporting the inclusion of this protein in EV MemProt Atlas.

EVMP confidence score

Annotation confidence score; open for threshold definitions.

Extremely high >= 0.85High >= 0.70Medium >= 0.55Low >= 0.40
UniProt IDProtein namesProtein classificationTransmembrane countRelated DiseasesMediation categoriesDownload
PRAXQ9BXM0PeriaxinDisease related genesHuman disease related genesPlasma proteinsFusion and delivery mediation10.50
PROM1O43490Prominin-1 (Antigen AC133) (Prominin-like protein 1) (CD antigen CD133)CD markersDisease related genesHuman disease related genes5Acute myeloid leukaemiaBrain cancerColorectal cancerClinical-translation mediationFusion and delivery mediation10.50
PTH1RQ03431Parathyroid hormone/parathyroid hormone-related peptide receptor (PTH/PTHrP type I receptor) (PTH/PTHr receptor) (Parathyroid hormone 1 receptor) (PTH1 receptor)Disease related genesFDA approved drug targetsG-protein coupled receptors7Hypo-parathyroidismLow bone mass disorderClinical-translation mediationFusion and delivery mediationMetabolism mediation10.50
PTPRBP23467Receptor-type tyrosine-protein phosphatase beta (Protein-tyrosine phosphatase beta) (R-PTP-beta) (EC 3.1.3.48) (Vascular endothelial protein tyrosine phosphatase) (VE-PTP)Cancer-related genesEnzymesPlasma proteins1Chronic arterial occlusive diseaseRetinopathyClinical-translation mediationFusion and delivery mediationImmune mediation10.50
RAB23Q9ULC3Ras-related protein Rab-23 (EC 3.6.5.2)Disease related genesHuman disease related genesPredicted intracellular proteinsFusion and delivery mediationMetabolism mediation10.50
RAF1P04049RAF proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (Proto-oncogene c-RAF) (cRaf) (Raf-1)Cancer-related genesDisease related genesEnzymesClinical-translation mediationFusion and delivery mediationImmune mediation10.50
RAGEQ15109Advanced glycosylation end product-specific receptor (Receptor for advanced glycosylation end products)Cancer-related genesPlasma proteinsPredicted membrane proteins1Alzheimer diseaseChronic kidney diseaseDementiaAdhesion and uptake mediationClinical-translation mediationFusion and delivery mediation10.50
RALAP11233Ras-related protein Ral-A (EC 3.6.5.2)Disease related genesEnzymesHuman disease related genesAdhesion and uptake mediationFusion and delivery mediationImmune mediation10.50
RASNP01111GTPase NRas (EC 3.6.5.2) (Transforming protein N-Ras)Cancer-related genesDisease related genesEnzymesColorectal cancerHead and neck cancerLung cancerClinical-translation mediationFusion and delivery mediationImmune mediation10.50
RIMS2Q9UQ26Regulating synaptic membrane exocytosis protein 2 (Rab-3-interacting molecule 2) (RIM 2) (Rab-3-interacting protein 3)Disease related genesHuman disease related genesPredicted intracellular proteinsFusion and delivery mediationReceptor-signaling mediation10.50
RIPK1Q13546Receptor-interacting serine/threonine-protein kinase 1 (EC 2.7.11.1) (Cell death protein RIP) (Receptor-interacting protein 1) (RIP-1)Disease related genesEnzymesHuman disease related genesAlzheimer diseaseCutaneous lupus erythematosusMalignant haematopoietic neoplasmClinical-translation mediationFusion and delivery mediationImmune mediation10.50
ROBO1Q9Y6N7Roundabout homolog 1 (Deleted in U twenty twenty) (H-Robo-1)Predicted intracellular proteinsPredicted membrane proteins1Adhesion and uptake mediationImmune mediationReceptor-signaling mediation10.50
ROM1Q03395Rod outer segment membrane protein 1 (ROSP1) (Tetraspanin-23) (Tspan-23)Disease related genesHuman disease related genesPlasma proteins4Other mediation10.50
RYR2Q92736Ryanodine receptor 2 (RYR-2) (RyR2) (hRYR-2) (Cardiac muscle ryanodine receptor) (Cardiac muscle ryanodine receptor-calcium release channel) (Type 2 ryanodine receptor)Disease related genesFDA approved drug targetsHuman disease related genes6Clinical-translation mediationFusion and delivery mediationMetabolism mediation10.50
S12A2P55011Solute carrier family 12 member 2 (Basolateral Na-K-Cl symporter) (Bumetanide-sensitive sodium-(potassium)-chloride cotransporter 2) (BSC2) (Na-K-2Cl cotransporter 1) (hNKCC1)Disease related genesFDA approved drug targetsHuman disease related genes12Clinical-translation mediationFusion and delivery mediationImmune mediation10.50
S28A1O00337Sodium/nucleoside cotransporter 1 (Concentrative nucleoside transporter 1) (CNT 1) (hCNT1) (Na(+)/nucleoside cotransporter 1) (Sodium-coupled nucleoside transporter 1) (Solute carrier family 28 member 1)Disease related genesMetabolic proteinsPotential drug targets13Fusion and delivery mediation10.50
S38A2Q96QD8Sodium-coupled neutral amino acid symporter 2 (Amino acid transporter A2) (Protein 40-9-1) (Solute carrier family 38 member 2) (System A amino acid transporter 2) (System A transporter 1) (System N amino acid transporter 2)Essential proteinsFDA approved drug targetsMetabolic proteins11Clinical-translation mediationFusion and delivery mediation10.50
S39AEQ15043Metal cation symporter ZIP14 (LIV-1 subfamily of ZIP zinc transporter 4) (LZT-Hs4) (Solute carrier family 39 member 14) (Zrt- and Irt-like protein 14) (ZIP-14)Disease related genesHuman disease related genesMetabolic proteins6Fusion and delivery mediationMetabolism mediationReceptor-signaling mediation10.50
S40A1Q9NP59Ferroportin (Ferroportin-1) (Iron-regulated transporter 1) (Solute carrier family 40 member 1)Disease related genesHuman disease related genesMetabolic proteins12Acute disease anaemiaAnemiaMyelodysplastic syndromeClinical-translation mediationFusion and delivery mediationImmune mediation10.50
S4A4Q9Y6R1Electrogenic sodium bicarbonate cotransporter 1 (Sodium bicarbonate cotransporter) (Na(+)/HCO3(-) cotransporter) (Solute carrier family 4 member 4) (kNBC1)Disease related genesHuman disease related genesMetabolic proteins12Clinical-translation mediationFusion and delivery mediation10.50
SC5A1P13866Sodium/glucose cotransporter 1 (Na(+)/glucose cotransporter 1) (High affinity sodium-glucose cotransporter) (Solute carrier family 5 member 1)Disease related genesFDA approved drug targetsHuman disease related genes14Clinical-translation mediationFusion and delivery mediation10.50
SC5A6Q9Y289Sodium-dependent multivitamin transporter (Na(+)-dependent multivitamin transporter) (hSMVT) (Solute carrier family 5 member 6)Disease related genesMetabolic proteinsPlasma proteins13Substance abuseClinical-translation mediationFusion and delivery mediationMetabolism mediation10.50
SCN9AQ15858Sodium channel protein type 9 subunit alpha (Neuroendocrine sodium channel) (hNE-Na) (Peripheral sodium channel 1) (PN1) (Sodium channel protein type IX subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.7)Disease related genesFDA approved drug targetsHuman disease related genes24AsthmaBipolar disorderChronic painClinical-translation mediationFusion and delivery mediation10.50
SCNNDP51172Epithelial sodium channel subunit delta (Delta-ENaC) (ENaCD) (Epithelial Na(+) channel subunit delta) (Amiloride-sensitive sodium channel subunit delta) (Delta-NaCH) (Nonvoltage-gated sodium channel 1 subunit delta) (SCNED)FDA approved drug targetsMetabolic proteinsPredicted intracellular proteins2Clinical-translation mediationFusion and delivery mediation10.50
SL9A3P48764Sodium/hydrogen exchanger 3 (Na(+)/H(+) exchanger 3) (NHE-3) (Solute carrier family 9 member 3)Disease related genesFDA approved drug targetsHuman disease related genes13Angina pectorisBreathing abnormalityCardiac arrhythmiaClinical-translation mediationFusion and delivery mediation10.50

376-400 of 792 proteins

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