Browse EV MemProt Atlas
Supporting publications (n)

Number of publications supporting the inclusion of this protein in EV MemProt Atlas.

EVMP confidence score

Annotation confidence score; open for threshold definitions.

Extremely high >= 0.85High >= 0.70Medium >= 0.55Low >= 0.40
UniProt IDProtein namesProtein classificationTransmembrane countRelated DiseasesMediation categoriesDownload
FZD1Q9UP38Frizzled-1 (Fz-1) (hFz1) (FzE1)Cancer-related genesG-protein coupled receptorsPlasma proteins7Adhesion and uptake mediationReceptor-signaling mediation90.63
ICAM1P05362Intercellular adhesion molecule 1 (ICAM-1) (Major group rhinovirus receptor) (CD antigen CD54)Cancer-related genesCandidate cardiovascular disease genesCD markers1Conjunctiva disorderCrohn diseaseIndeterminate colitisAdhesion and uptake mediationClinical-translation mediationFusion and delivery mediation90.63
IL2RGP31785Cytokine receptor common subunit gamma (Interleukin-2 receptor subunit gamma) (IL-2 receptor subunit gamma) (IL-2R subunit gamma) (IL-2RG) (gammaC) (p64) (CD antigen CD132)Cancer-related genesCD markersDisease related genes1Adhesion and uptake mediationClinical-translation mediationFusion and delivery mediation90.63
ITA2BP08514Integrin alpha-IIb (GPalpha IIb) (GPIIb) (Platelet membrane glycoprotein IIb) (CD antigen CD41) [Cleaved into: Integrin alpha-IIb heavy chain; Integrin alpha-IIb light chain, form 1; Integrin alpha-IIb light chain, form 2]Cancer-related genesCandidate cardiovascular disease genesCD markers1Adhesion and uptake mediationClinical-translation mediationFusion and delivery mediation90.63
KDF1Q8NAX2Keratinocyte differentiation factor 1Disease related genesHuman disease related genesPredicted intracellular proteinsFusion and delivery mediation90.63
PPBNP10696Alkaline phosphatase, germ cell type (EC 3.1.3.1) (ALP-1) (Alkaline phosphatase Nagao isozyme) (Alkaline phosphatase, placental-like) (Germ cell alkaline phosphatase) (GCAP) (Placental alkaline phosphatase-like) (PLAP-like)EnzymesFDA approved drug targetsMetabolic proteinsClinical-translation mediationMetabolism mediation90.63
SCRIBQ14160Protein scribble homolog (Scribble) (hScrib) (Protein LAP4)Disease related genesPredicted intracellular proteinsAdhesion and uptake mediationClinical-translation mediationFusion and delivery mediation90.63
TNR14Q92956Tumor necrosis factor receptor superfamily member 14 (Herpes virus entry mediator A) (Herpesvirus entry mediator A) (HveA) (Tumor necrosis factor receptor-like 2) (TR2) (CD antigen CD270)Cancer-related genesCD markersHuman disease related genes1Adhesion and uptake mediationFusion and delivery mediationImmune mediation90.63
ADA10O14672Disintegrin and metalloproteinase domain-containing protein 10 (ADAM 10) (EC 3.4.24.81) (CDw156) (Kuzbanian protein homolog) (Mammalian disintegrin-metalloprotease) (CD antigen CD156c)Cancer-related genesCD markersDisease related genes1Breast cancerSolid tumour/cancerAdhesion and uptake mediationClinical-translation mediationFusion and delivery mediation80.63
NIBA1Q9BZQ8Protein Niban 1 (Cell growth-inhibiting gene 39 protein) (Protein FAM129A)Cancer-related genesPredicted intracellular proteinsOther mediation80.63
APOBRQ0VD83Apolipoprotein B receptor (Apolipoprotein B-100 receptor) (Apolipoprotein B-48 receptor) (Apolipoprotein B48 receptor) (apoB-48R)Predicted intracellular proteinsFusion and delivery mediation70.63
CADM4Q8NFZ8Cell adhesion molecule 4 (Immunoglobulin superfamily member 4C) (IgSF4C) (Nectin-like protein 4) (NECL-4) (TSLC1-like protein 2)Predicted membrane proteins1Adhesion and uptake mediationReceptor-signaling mediation70.63
DSC2Q02487Desmocollin-2 (Cadherin family member 2) (Desmocollin-3) (Desmosomal glycoprotein II) (Desmosomal glycoprotein III)Disease related genesHuman disease related genesPlasma proteins1Adhesion and uptake mediationFusion and delivery mediation70.63
MUC1P15941Mucin-1 (MUC-1) (Breast carcinoma-associated antigen DF3) (Cancer antigen 15-3) (CA 15-3) (Carcinoma-associated mucin) (Episialin) (H23AG) (Krebs von den Lungen-6) (KL-6) (PEMT) (Peanut-reactive urinary mucin) (PUM) (Polymorphic epithelial mucin) (PEM) (Tumor-associated epithelial membrane antigen) (EMA) (Tumor-associated mucin) (CD antigen CD227) [Cleaved into: Mucin-1 subunit alpha (MUC1-NT) (MUC1-alpha); Mucin-1 subunit beta (MUC1-beta) (MUC1-CT)]Cancer-related genesCD markersDisease related genes1Acute myeloid leukaemiaBipolar disorderBrain cancerAdhesion and uptake mediationClinical-translation mediationFusion and delivery mediation70.63
PDE4DQ084993',5'-cyclic-AMP phosphodiesterase 4D (EC 3.1.4.53) (DPDE3) (PDE43) (cAMP-specific phosphodiesterase 4D)Disease related genesEnzymesFDA approved drug targetsAcute upper respiratory infectionAllergic/hypersensitivity disorderAlzheimer diseaseClinical-translation mediationFusion and delivery mediationImmune mediation70.63
SRC8Q14247Src substrate cortactin (Amplaxin) (Oncogene EMS1)Cancer-related genesPlasma proteinsPredicted intracellular proteinsAdhesion and uptake mediationFusion and delivery mediationReceptor-signaling mediation70.63
UFOP30530Tyrosine-protein kinase receptor UFO (EC 2.7.10.1) (AXL oncogene)Disease related genesEnzymesFDA approved drug targets1Acute myeloid leukaemiaBreast cancerKaposi sarcomaAdhesion and uptake mediationClinical-translation mediationImmune mediation70.63
XRN1Q8IZH25'-3' exoribonuclease 1 (EC 3.1.13.-) (Strand-exchange protein 1 homolog)Essential proteinsPredicted intracellular proteinsClinical-translation mediation70.63
AA1RP30542Adenosine receptor A1FDA approved drug targetsG-protein coupled receptorsPredicted membrane proteins7Acute diabete complicationAllergic/hypersensitivity disorderCardiac arrhythmiaClinical-translation mediationFusion and delivery mediationImmune mediation60.63
ANO10Q9NW15Anoctamin-10 (Transmembrane protein 16K)Disease related genesHuman disease related genesPotential drug targets8Clinical-translation mediationFusion and delivery mediation60.63
ARHGCQ9NZN5Rho guanine nucleotide exchange factor 12 (Leukemia-associated RhoGEF)Cancer-related genesDisease related genesPredicted intracellular proteinsReceptor-signaling mediation60.63
CAH14Q9ULX7Carbonic anhydrase 14 (EC 4.2.1.1) (Carbonate dehydratase XIV) (Carbonic anhydrase XIV) (CA-XIV)EnzymesFDA approved drug targetsMetabolic proteins1Clinical-translation mediationFusion and delivery mediationMetabolism mediation60.63
CSF1RP07333Macrophage colony-stimulating factor 1 receptor (CSF-1 receptor) (CSF-1-R) (CSF-1R) (M-CSF-R) (EC 2.7.10.1) (Proto-oncogene c-Fms) (CD antigen CD115)Cancer-related genesCD markersDisease related genes1Alzheimer diseaseBone/articular cartilage neoplasmDiabetes mellitusClinical-translation mediationImmune mediationReceptor-signaling mediation60.63
FGRP09769Tyrosine-protein kinase Fgr (EC 2.7.10.2) (Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog) (Proto-oncogene c-Fgr) (p55-Fgr) (p58-Fgr) (p58c-Fgr)Disease related genesEnzymesPlasma proteinsClinical-translation mediationFusion and delivery mediationImmune mediation60.63
HRH1P35367Histamine H1 receptor (H1-R) (H1R) (HH1R)FDA approved drug targetsG-protein coupled receptorsPredicted intracellular proteins7Clinical-translation mediationReceptor-signaling mediation60.63

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