Browse EV MemProt Atlas
Supporting publications (n)
Number of publications supporting the inclusion of this protein in EV MemProt Atlas.
EVMP confidence score
Annotation confidence score; open for threshold definitions.
Extremely high >= 0.85High >= 0.70Medium >= 0.55Low >= 0.40| UniProt ID | Protein names | Protein classification | Transmembrane count | Related Diseases | Mediation categories | Download | ||||
|---|---|---|---|---|---|---|---|---|---|---|
| I15RA | Q13261 | Interleukin-15 receptor subunit alpha (IL-15 receptor subunit alpha) (IL-15R-alpha) (IL-15RA) (CD antigen CD215) [Cleaved into: Soluble interleukin-15 receptor subunit alpha (sIL-15 receptor subunit alpha) (sIL-15R-alpha) (sIL-15RA)] | CD markersPredicted intracellular proteinsPredicted membrane proteins | 1 | Acute myeloid leukaemiaBladder cancerColorectal cancer | Clinical-translation mediationImmune mediation | 1 | 0.50 | ||
| ICAM2 | P13598 | Intercellular adhesion molecule 2 (ICAM-2) (CD antigen CD102) | CD markersPlasma proteinsPredicted intracellular proteins | 1 | Immune mediation | 1 | 0.50 | |||
| ICEF1 | Q8WWN9 | Interactor protein for cytohesin exchange factors 1 (Phosphoinositide-binding protein PIP3-E) | Predicted intracellular proteins | Other mediation | 1 | 0.50 | ||||
| IGF1R | P08069 | Insulin-like growth factor 1 receptor (EC 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) (CD antigen CD221) [Cleaved into: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain] | Cancer-related genesCD markersDisease related genes | 1 | Adrenal cancerBreast cancerChronic kidney disease | Clinical-translation mediationFusion and delivery mediationMetabolism mediation | 1 | 0.50 | ||
| IL21R | Q9HBE5 | Interleukin-21 receptor (IL-21 receptor) (IL-21R) (Novel interleukin receptor) (CD antigen CD360) | Cancer-related genesCD markersDisease related genes | 1 | Crohn diseasePostoperative inflammationSolid tumour/cancer | Clinical-translation mediationFusion and delivery mediationImmune mediation | 1 | 0.50 | ||
| IL31R | Q8NI17 | Interleukin-31 receptor subunit alpha (IL-31 receptor subunit alpha) (IL-31R subunit alpha) (IL-31R-alpha) (IL-31RA) (Cytokine receptor-like 3) (GLM-R) (hGLM-R) (Gp130-like monocyte receptor) (Gp130-like receptor) (ZcytoR17) | Disease related genesHuman disease related genesPredicted intracellular proteins | 1 | Fusion and delivery mediationImmune mediation | 1 | 0.50 | |||
| IL6RB | P40189 | Interleukin-6 receptor subunit beta (IL-6 receptor subunit beta) (IL-6R subunit beta) (IL-6R-beta) (IL-6RB) (CDw130) (Interleukin-6 signal transducer) (Membrane glycoprotein 130) (gp130) (Oncostatin-M receptor subunit alpha) (CD antigen CD130) | Cancer-related genesCandidate cardiovascular disease genesCD markers | 1 | Adhesion and uptake mediationFusion and delivery mediationImmune mediation | 1 | 0.50 | |||
| ILDR2 | Q71H61 | Immunoglobulin-like domain-containing receptor 2 (Angulin-3) | Predicted intracellular proteinsPredicted membrane proteins | 1 | Solid tumour/cancer | Adhesion and uptake mediationClinical-translation mediationFusion and delivery mediation | 1 | 0.50 | ||
| INGR1 | P15260 | Interferon gamma receptor 1 (IFN-gamma receptor 1) (IFN-gamma-R1) (CDw119) (Interferon gamma receptor alpha-chain) (IFN-gamma-R-alpha) (CD antigen CD119) | CD markersDisease related genesFDA approved drug targets | 1 | Clinical-translation mediationImmune mediation | 1 | 0.50 | |||
| IQGA1 | P46940 | Ras GTPase-activating-like protein IQGAP1 (p195) | Plasma proteinsPredicted intracellular proteins | Adhesion and uptake mediationClinical-translation mediationFusion and delivery mediation | 1 | 0.50 | ||||
| IRAG2 | Q12912 | Inositol 1,4,5-triphosphate receptor associated 2 (Lymphoid-restricted membrane protein) (Protein Jaw1) [Cleaved into: Processed inositol 1,4,5-triphosphate receptor associated 2] | Predicted intracellular proteinsPredicted membrane proteinsTransporters | 1 | Fusion and delivery mediationImmune mediation | 1 | 0.50 | |||
| ITA3 | P26006 | Integrin alpha-3 (CD49 antigen-like family member C) (FRP-2) (Galactoprotein B3) (GAPB3) (VLA-3 subunit alpha) (CD antigen CD49c) [Cleaved into: Integrin alpha-3 heavy chain; Integrin alpha-3 light chain] | Cancer-related genesCD markersDisease related genes | 1 | Adhesion and uptake mediationFusion and delivery mediationImmune mediation | 1 | 0.50 | |||
| ITA4 | P13612 | Integrin alpha-4 (CD49 antigen-like family member D) (Integrin alpha-IV) (VLA-4 subunit alpha) (CD antigen CD49d) | 1 | AsthmaCerebral ischaemic strokeCrohn disease | Adhesion and uptake mediationClinical-translation mediationFusion and delivery mediation | 1 | 0.50 | |||
| ITA7 | Q13683 | Integrin alpha-7 [Cleaved into: Integrin alpha-7 heavy chain; Integrin alpha-7 light chain; Integrin alpha-7 70 kDa form] | Disease related genesHuman disease related genesPotential drug targets | 1 | Adhesion and uptake mediationFusion and delivery mediationImmune mediation | 1 | 0.50 | |||
| ITB2 | P05107 | Integrin beta-2 (Cell surface adhesion glycoproteins LFA-1/CR3/p150,95 subunit beta) (Complement receptor C3 subunit beta) (CD antigen CD18) | CD markersDisease related genesHuman disease related genes | 1 | Cerebral ischaemiaInnate/adaptive immunodeficiencyIschaemic/haemorrhagic stroke | Adhesion and uptake mediationClinical-translation mediationFusion and delivery mediation | 1 | 0.50 | ||
| ITB5 | P18084 | Integrin beta-5 | Cancer-related genesPlasma proteinsPredicted intracellular proteins | 1 | Adhesion and uptake mediationFusion and delivery mediationImmune mediation | 1 | 0.50 | |||
| ITB7 | P26010 | Integrin beta-7 (Gut homing receptor beta subunit) | 1 | Crohn diseaseUlcerative colitis | Adhesion and uptake mediationClinical-translation mediationImmune mediation | 1 | 0.50 | |||
| ITB8 | P26012 | Integrin beta-8 | Cancer-related genesPredicted membrane proteins | 1 | Chronic kidney disease | Adhesion and uptake mediationClinical-translation mediationImmune mediation | 1 | 0.50 | ||
| IYD1 | Q6PHW0 | Iodotyrosine deiodinase 1 (IYD-1) (EC 1.21.1.1) (Iodotyrosine dehalogenase 1) | Disease related genesEnzymesHuman disease related genes | 1 | Metabolism mediation | 1 | 0.50 | |||
| JAG1 | P78504 | Protein jagged-1 (Jagged1) (hJ1) (CD antigen CD339) | CD markersDisease related genesHuman disease related genes | 1 | Adhesion and uptake mediationClinical-translation mediationFusion and delivery mediation | 1 | 0.50 | |||
| JAML | Q86YT9 | Junctional adhesion molecule-like (Adhesion molecule interacting with CXADR antigen 1) (Dendritic cell-specific protein CREA7-1) | Predicted intracellular proteinsPredicted membrane proteins | 1 | Adhesion and uptake mediationFusion and delivery mediationImmune mediation | 1 | 0.50 | |||
| JIP1 | Q9UQF2 | C-Jun-amino-terminal kinase-interacting protein 1 (JIP-1) (JNK-interacting protein 1) (Islet-brain 1) (IB-1) (JNK MAP kinase scaffold protein 1) (Mitogen-activated protein kinase 8-interacting protein 1) | Cancer-related genesDisease related genesPlasma proteins | Clinical-translation mediationImmune mediationReceptor-signaling mediation | 1 | 0.50 | ||||
| KCNA6 | P17658 | Potassium voltage-gated channel subfamily A member 6 (Voltage-gated potassium channel HBK2) (Voltage-gated potassium channel subunit Kv1.6) | 6 | Fusion and delivery mediation | 1 | 0.50 | ||||
| KCNA7 | Q96RP8 | Potassium voltage-gated channel subfamily A member 7 (Voltage-gated potassium channel subunit Kv1.7) | 6 | Fusion and delivery mediation | 1 | 0.50 | ||||
| KCNB2 | Q92953 | Potassium voltage-gated channel subfamily B member 2 (Voltage-gated potassium channel subunit Kv2.2) | 6 | Fusion and delivery mediation | 1 | 0.50 |