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E.g. CD9; CD81
E.g. CD9; CD81
E.g. Brain cancer; Lung cancer
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28 records.

Frequency:
literature support frequency.
EVMP score:
annotation confidence score.
Protein symbolUniProt IDProtein namesProtein classificationRelated DiseasesFrequencyEVMP scoreDownload
TUBP50607Tubby protein homologDisease related genesPredicted intracellular proteinsBladder cancer; Brain cancer; Breast cancer; Central nervous system disease; Epidermal dysplasias; Gout; Immune system disease; Ovarian cancer; Pancreatic cancer; Sarcoma; Solid tumour/cancer60.50
TNR6P25445Tumor necrosis factor receptor superfamily member 6 (Apo-1 antigen) (Apoptosis-mediating surface antigen FAS) (FASLG receptor) (CD antigen CD95)Cancer-related genesCandidate cardiovascular disease genesCD markersDisease related genesHuman disease related genesPredicted intracellular proteinsPredicted membrane proteinsPredicted secreted proteinsBrain cancer; Cerebral ischaemia; Mature T-cell lymphoma; Multiple myeloma; Ovarian cancer; Postoperative inflammation; Rheumatoid arthritis; Solid tumour/cancer10.50
TNR5P25942Tumor necrosis factor receptor superfamily member 5 (B-cell surface antigen CD40) (Bp50) (CD40L receptor) (CDw40) (CD antigen CD40)Cancer-related genesCD markersDisease related genesHuman disease related genesPredicted membrane proteinsPredicted secreted proteinsBrain cancer; Crohn disease; Diabetes mellitus; Lupus erythematosus; Mature B-cell leukaemia; Melanoma; Motor neuron disease; Multiple sclerosis; Myasthenia gravis; Ovarian cancer; Rheumatoid arthritis; Sjogren syndrome; Solid tumour/cancer; Thrombocytopenia; Thyrotoxicosis; Transplant rejection50.38
TGFR1P36897TGF-beta receptor type-1 (TGFR-1) (EC 2.7.11.30) (Activin A receptor type II-like protein kinase of 53kD) (Activin receptor-like kinase 5) (ALK-5) (ALK5) (Serine/threonine-protein kinase receptor R4) (SKR4) (TGF-beta type I receptor) (Transforming growth factor-beta receptor type I) (TGF-beta receptor type I) (TbetaR-I)Disease related genesEnzymesHuman disease related genesPotential drug targetsPredicted intracellular proteinsPredicted membrane proteinsArterial occlusive disease; Brain cancer; Cachexia; Fibrosis; Idiopathic interstitial pneumonitis; Liver cancer; Lung cancer; Myelodysplastic syndrome; Myeloproliferative neoplasm; Pancreatic cancer; Pulmonary disease; Solid tumour/cancer; Systemic sclerosis; Ureteral cancer10.50
TGFB1P01137Transforming growth factor beta-1 proprotein [Cleaved into: Latency-associated peptide (LAP); Transforming growth factor beta-1 (TGF-beta-1)]Human disease related genesPredicted secreted proteinsArterial occlusive disease; Brain cancer; Idiopathic interstitial pneumonitis; Lesion; Liver cancer; Lung cancer; Osteoarthritis; Pancreatic cancer; Retinopathy; Rheumatoid arthritis; Solid tumour/cancer; Systemic sclerosis200.60
SRCP12931Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (Proto-oncogene c-Src) (pp60c-src) (p60-Src)Cancer-related genesDisease related genesEnzymesFDA approved drug targetsHuman disease related genesPlasma proteinsPredicted intracellular proteinsTransportersAcute myeloid leukaemia; BCR-ABL1-negative chronic myeloid leukaemia; Brain cancer; Breast cancer; Cardiovascular disease; Cervical cancer; Chronic obstructive pulmonary disease; Endometrial cancer; Epidermal dysplasias; Fallopian tube cancer; Gastrointestinal stromal tumour; Gram-positive bacterial infection; Ischemia; Leiomyosarcoma; Low bone mass disorder; Malignant digestive organ neoplasm; Malignant haematopoietic neoplasm; Mature B-cell leukaemia; Metastatic digestive system neoplasm; Motor neuron disease; Multiple myeloma; Multiple sclerosis; Myeloproliferative neoplasm; Nasopharyngeal cancer; Osteosarcoma; Ovarian cancer; Pancreatic cancer; Parkinsonism; Peritoneal cancer; Postoperative inflammation; Sarcoma; Solid tumour/cancer; Synovial sarcoma10.50
SMOQ99835Protein smoothened (Protein Gx)Cancer-related genesDisease related genesFDA approved drug targetsG-protein coupled receptorsHuman disease related genesPlasma proteinsPredicted membrane proteinsTransportersBasal cell carcinoma; Brain cancer; Chronic myelomonocytic leukaemia; Ovarian cancer; Skin cancer; Solid tumour/cancer10.50
PROM1O43490Prominin-1 (Antigen AC133) (Prominin-like protein 1) (CD antigen CD133)CD markersDisease related genesHuman disease related genesPotential drug targetsPredicted intracellular proteinsPredicted membrane proteinsTransportersAcute myeloid leukaemia; Brain cancer; Colorectal cancer; Liver cancer; Ovarian cancer; Pancreatic cancer; Solid tumour/cancer10.50
PK3CGP48736Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (PI3-kinase subunit gamma) (PI3K-gamma) (PI3Kgamma) (PtdIns-3-kinase subunit gamma) (EC 2.7.1.137) (EC 2.7.1.153) (EC 2.7.1.154) (Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit gamma) (PtdIns-3-kinase subunit p110-gamma) (p110gamma) (Phosphoinositide-3-kinase catalytic gamma polypeptide) (Serine/threonine protein kinase PIK3CG) (EC 2.7.11.1) (p120-PI3K)Cancer-related genesDisease related genesEnzymesFDA approved drug targetsMetabolic proteinsPredicted intracellular proteinsCOVID-19; Follicular lymphoma; Adrenal cancer; Asthma; Bacterial infection; B-cell lymphoma; BCR-ABL1-negative chronic myeloid leukaemia; Bladder cancer; Brain cancer; Breast cancer; Cardiovascular disease; Central nervous system disease; Colorectal cancer; Diffuse large B-cell lymphoma; Endometrial cancer; Head and neck cancer; Innate/adaptive immunodeficiency; Liver cancer; Lymphoma; Malignant haematopoietic neoplasm; Mature B-cell leukaemia; Melanoma; Metastatic lymph node neoplasm; Myelodysplastic syndrome; Myocardial infarction; Pain; Peritoneal cancer; Pleural mesothelioma; Postoperative inflammation; Prostate cancer; Rheumatoid arthritis; Solid tumour/cancer; Type 2 diabetes mellitus50.50
PGFRAP16234Platelet-derived growth factor receptor alpha (PDGF-R-alpha) (PDGFR-alpha) (EC 2.7.10.1) (Alpha platelet-derived growth factor receptor) (Alpha-type platelet-derived growth factor receptor) (CD140 antigen-like family member A) (CD140a antigen) (Platelet-derived growth factor alpha receptor) (Platelet-derived growth factor receptor 2) (PDGFR-2) (CD antigen CD140a)Cancer-related genesCD markersDisease related genesEnzymesFDA approved drug targetsHuman disease related genesPlasma proteinsPredicted intracellular proteinsPredicted membrane proteinsRAS pathway related proteinsAcute myeloid leukaemia; BCR-ABL1-negative chronic myeloid leukaemia; Brain cancer; Breast cancer; Colon cancer; Colorectal cancer; Gastrointestinal stromal tumour; Gram-positive bacterial infection; Kaposi sarcoma; Lung cancer; Malignant digestive organ neoplasm; Mastocytosis; Multiple myeloma; Myelodysplastic syndrome; Pancreatic cancer; Prostate cancer; Solid tumour/cancer; Stomach cancer; Thrombocytopenia30.50
MUC1P15941Mucin-1 (MUC-1) (Breast carcinoma-associated antigen DF3) (Cancer antigen 15-3) (CA 15-3) (Carcinoma-associated mucin) (Episialin) (H23AG) (Krebs von den Lungen-6) (KL-6) (PEMT) (Peanut-reactive urinary mucin) (PUM) (Polymorphic epithelial mucin) (PEM) (Tumor-associated epithelial membrane antigen) (EMA) (Tumor-associated mucin) (CD antigen CD227) [Cleaved into: Mucin-1 subunit alpha (MUC1-NT) (MUC1-alpha); Mucin-1 subunit beta (MUC1-beta) (MUC1-CT)]Cancer-related genesCD markersDisease related genesHuman disease related genesPredicted intracellular proteinsPredicted membrane proteinsPredicted secreted proteinsAcute myeloid leukaemia; Bipolar disorder; Brain cancer; Breast cancer; Cervical cancer; Colorectal cancer; Esophageal cancer; Liver cancer; Lung cancer; Multiple myeloma; Myelodysplastic syndrome; Pancreatic cancer; Solid tumour/cancer; Stomach cancer70.63
METP08581Hepatocyte growth factor receptor (HGF receptor) (EC 2.7.10.1) (HGF/SF receptor) (Proto-oncogene c-Met) (Scatter factor receptor) (SF receptor) (Tyrosine-protein kinase Met)Cancer-related genesDisease related genesEnzymesFDA approved drug targetsHuman disease related genesPlasma proteinsPredicted intracellular proteinsPredicted membrane proteinsPredicted secreted proteinsRAS pathway related proteinsTransportersAlzheimer disease; Biliary tract cancer; Brain cancer; Breast cancer; Cardiovascular disease; Chronic arterial occlusive disease; Colorectal cancer; Fibrosis; Glaucoma; Head and neck cancer; Heart disease; Injury; Liver cancer; Liver disease; Lung cancer; Melanoma; Metastatic lymph node neoplasm; Nasopharyngitis; Non-small-cell lung cancer; Ovarian cancer; Renal cell carcinoma; Sarcoma; Solid tumour/cancer; Stomach cancer; Thyroid cancer30.38
MERTKQ12866Tyrosine-protein kinase Mer (EC 2.7.10.1) (Proto-oncogene c-Mer) (Receptor tyrosine kinase MerTK)Disease related genesEnzymesHuman disease related genesPlasma proteinsPotential drug targetsPredicted intracellular proteinsPredicted membrane proteinsAcute myeloid leukaemia; Alzheimer disease; Brain cancer; Mature B-cell lymphoma; Myelodysplastic syndrome; Solid tumour/cancer10.50
L1CAMP32004Neural cell adhesion molecule L1 (N-CAM-L1) (NCAM-L1) (CD antigen CD171)CD markersDisease related genesHuman disease related genesPlasma proteinsPredicted intracellular proteinsPredicted membrane proteinsAdrenal cancer; Brain cancer20.50
KITP10721Mast/stem cell growth factor receptor Kit (SCFR) (EC 2.7.10.1) (Piebald trait protein) (PBT) (Proto-oncogene c-Kit) (Tyrosine-protein kinase Kit) (p145 c-kit) (v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog) (CD antigen CD117)Cancer-related genesCD markersDisease related genesEnzymesFDA approved drug targetsHuman disease related genesPlasma proteinsPredicted intracellular proteinsPredicted membrane proteinsRAS pathway related proteinsAcute myeloid leukaemia; Alzheimer disease; Bone/articular cartilage neoplasm; Brain cancer; Colorectal cancer; Gastrointestinal stromal tumour; Inflammatory arthropathy; Liver cancer; Lung cancer; Malignant intestine neoplasm; Mastocytosis; Mature B-cell lymphoma; Multiple myeloma; Myelodysplastic syndrome; Myeloproliferative neoplasm; Phakomatoses/hamartoneoplastic syndrome; Postoperative inflammation; Renal cell carcinoma; Solid tumour/cancer; Thrombocytopenia; Transplanted organ/tissue10.50
ITB1P05556Integrin beta-1 (Fibronectin receptor subunit beta) (Glycoprotein IIa) (GPIIA) (VLA-4 subunit beta) (CD antigen CD29)Cancer-related genesCD markersFDA approved drug targetsPlasma proteinsPredicted intracellular proteinsPredicted membrane proteinsTransportersBrain cancer; Lung cancer; Retinopathy30.50
IL2RBP14784Interleukin-2 receptor subunit beta (IL-2 receptor subunit beta) (IL-2R subunit beta) (IL-2RB) (High affinity IL-2 receptor subunit beta) (Interleukin-15 receptor subunit beta) (p70-75) (p75) (CD antigen CD122)Cancer-related genesCD markersDisease related genesFDA approved drug targetsHuman disease related genesPredicted membrane proteinsTransportersBladder cancer; Brain cancer; Colorectal cancer; Head and neck cancer; Human immunodeficiency virus disease; Melanoma; Renal cell carcinoma; Sarcoma; Solid tumour/cancer10.25
I13R2Q14627Interleukin-13 receptor subunit alpha-2 (IL-13 receptor subunit alpha-2) (IL-13R subunit alpha-2) (IL-13R-alpha-2) (IL-13RA2) (Interleukin-13-binding protein) (CD antigen CD213a2)Asthma; Brain cancer; Oesophagitis10.38
FASP49327Fatty acid synthase (EC 2.3.1.85) (Type I fatty acid synthase) [Includes: [Acyl-carrier-protein] S-acetyltransferase (EC 2.3.1.38); [Acyl-carrier-protein] S-malonyltransferase (EC 2.3.1.39); 3-oxoacyl-[acyl-carrier-protein] synthase (EC 2.3.1.41); 3-oxoacyl-[acyl-carrier-protein] reductase (EC 1.1.1.100); 3-hydroxyacyl-[acyl-carrier-protein] dehydratase (EC 4.2.1.59); Enoyl-[acyl-carrier-protein] reductase (EC 1.3.1.39); Acyl-[acyl-carrier-protein] hydrolase (EC 3.1.2.14)]Cancer-related genesEnzymesMetabolic proteinsPlasma proteinsPredicted intracellular proteinsBrain cancer; Colon cancer; concerning food/fluid intake symptom; Fungal infection; Gram-positive bacterial infection; Hepatic fibrosis/cirrhosis; Non-alcoholic fatty liver disease; Obesity; Solid tumour/cancer20.38
EPHB4P54760Ephrin type-B receptor 4 (EC 2.7.10.1) (Hepatoma transmembrane kinase) (Tyrosine-protein kinase TYRO11)Cancer-related genesDisease related genesEnzymesHuman disease related genesPlasma proteinsPotential drug targetsPredicted intracellular proteinsPredicted membrane proteinsTransportersBrain cancer; Cystic/dysplastic kidney disease; Lung cancer; Metastatic meninges neoplasm; Metastatic tumour; Solid tumour/cancer20.25
EPHA3P29320Ephrin type-A receptor 3 (EC 2.7.10.1) (EPH-like kinase 4) (EK4) (hEK4) (HEK) (Human embryo kinase) (Tyrosine-protein kinase TYRO4) (Tyrosine-protein kinase receptor ETK1) (Eph-like tyrosine kinase 1)Cancer-related genesDisease related genesEnzymesPotential drug targetsPredicted intracellular proteinsPredicted membrane proteinsAcute myeloid leukaemia; Brain cancer; Malignant haematopoietic neoplasm; Myelodysplastic syndrome10.50
EPHA2P29317Ephrin type-A receptor 2 (EC 2.7.10.1) (Epithelial cell kinase) (Tyrosine-protein kinase receptor ECK)Brain cancer; Solid tumour/cancer10.50
EGLNP17813Endoglin (CD antigen CD105)Cancer-related genesCandidate cardiovascular disease genesCD markersDisease related genesHuman disease related genesPlasma proteinsPredicted membrane proteinsAngiosarcoma; Brain cancer; Breast cancer; Fallopian tube cancer; Gynecologic cancer; Kaposi sarcoma; Liver cancer; Lung cancer; Non-small-cell lung cancer; Ovarian cancer; Peritoneal cancer; Renal cell carcinoma; Retinopathy10.50
EGFRP00533Epidermal growth factor receptor (EC 2.7.10.1) (Proto-oncogene c-ErbB-1) (Receptor tyrosine-protein kinase erbB-1)Cancer-related genesDisease related genesEnzymesFDA approved drug targetsHuman disease related genesMetabolic proteinsPlasma proteinsPredicted membrane proteinsPredicted secreted proteinsRAS pathway related proteinsTransportersAngina pectoris; Brain cancer; Breast cancer; Cerebral ischaemia; Chronic pain; Colon cancer; Colorectal cancer; Cryptosporidiosis; Diabetic foot ulcer; Diffuse large B-cell lymphoma; Digestive system disease; Esophageal cancer; Gram-positive bacterial infection; Head and neck cancer; Hepatitis virus infection; Hypopharyngeal cancer; Intracerebral haemorrhage; Ischemia; Liver cancer; Lung cancer; Lymphoma; Malignant mesenchymal neoplasm; Mature B-cell leukaemia; Melanoma; Metastatic biliary tract neoplasms; Metastatic lymph node neoplasm; Myelodysplastic syndrome; Nasopharyngeal cancer; Non-small-cell lung cancer; Pancreatic cancer; Psoriasis; Renal cell carcinoma; Skin postprocedural disorder; Solid tumour/cancer; Spinal cord/cranial nerve neoplasm; Stomach cancer; Testicular cancer; Unspecific body region injury; Urethral cancer10.50
DAFP08174Complement decay-accelerating factor (CD antigen CD55)Blood group antigen proteinsCD markersDisease related genesHuman disease related genesPlasma proteinsPredicted intracellular proteinsPredicted membrane proteinsPredicted secreted proteinsBladder cancer; Brain cancer; Colorectal cancer; Lung cancer; Melanoma; Prostate cancer; Stomach cancer340.63

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