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E.g. CD9; CD81
E.g. CD9 antigen; CD81 antigen
E.g. Brain cancer; Lung cancer
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Supporting publications (n)

Number of publications supporting the inclusion of this protein in EV MemProt Atlas.

EVMP confidence score

Annotation confidence score; open for threshold definitions.

Extremely high >= 0.85High >= 0.70Medium >= 0.55Low >= 0.40
Entry nameUniProt IDProtein namesProtein classificationRelated DiseasesSupporting publications (n)EVMP confidence scoreDownload
CD47Q08722Leukocyte surface antigen CD47 (Antigenic surface determinant protein OA3) (Integrin-associated protein) (IAP) (Protein MER6) (CD antigen CD47)CD markersPredicted intracellular proteinsPredicted membrane proteinsAcute myeloid leukaemia; B-cell lymphoma; Colorectal cancer; Diffuse large B-cell lymphoma; Leukaemia; Lymphoma; Malignant haematopoietic neoplasm; Melanoma; Multiple myeloma; Mycosis fungoides; Myelodysplastic syndrome; Neuroendocrine carcinoma; Non-small-cell lung cancer; Ovarian cancer; Solid tumour/cancer; Squamous cell carcinoma; Stomach cancer290.88
TACD2P09758Tumor-associated calcium signal transducer 2 (Cell surface glycoprotein Trop-2) (Membrane component chromosome 1 surface marker 1) (Pancreatic carcinoma marker protein GA733-1)Disease related genesFDA approved drug targetsHuman disease related genesBreast cancer; Non-small-cell lung cancer; Solid tumour/cancer; Ureteral cancer160.72
DAFP08174Complement decay-accelerating factor (CD antigen CD55)Blood group antigen proteinsCD markersDisease related genesBladder cancer; Brain cancer; Colorectal cancer; Lung cancer; Melanoma; Prostate cancer; Stomach cancer340.63
MARCSP29966Myristoylated alanine-rich C-kinase substrate (MARCKS) (Protein kinase C substrate, 80 kDa protein, light chain) (80K-L protein) (PKCSL)Plasma proteinsPredicted intracellular proteinsChronic obstructive pulmonary disease; Lung cancer100.63
MUC1P15941Mucin-1 (MUC-1) (Breast carcinoma-associated antigen DF3) (Cancer antigen 15-3) (CA 15-3) (Carcinoma-associated mucin) (Episialin) (H23AG) (Krebs von den Lungen-6) (KL-6) (PEMT) (Peanut-reactive urinary mucin) (PUM) (Polymorphic epithelial mucin) (PEM) (Tumor-associated epithelial membrane antigen) (EMA) (Tumor-associated mucin) (CD antigen CD227) [Cleaved into: Mucin-1 subunit alpha (MUC1-NT) (MUC1-alpha); Mucin-1 subunit beta (MUC1-beta) (MUC1-CT)]Cancer-related genesCD markersDisease related genesAcute myeloid leukaemia; Bipolar disorder; Brain cancer; Breast cancer; Cervical cancer; Colorectal cancer; Esophageal cancer; Liver cancer; Lung cancer; Multiple myeloma; Myelodysplastic syndrome; Pancreatic cancer; Solid tumour/cancer; Stomach cancer70.63
UFOP30530Tyrosine-protein kinase receptor UFO (EC 2.7.10.1) (AXL oncogene)Disease related genesEnzymesFDA approved drug targetsAcute myeloid leukaemia; Breast cancer; Kaposi sarcoma; Lung cancer; Mature B-cell leukaemia; Metastatic malignant neoplasm; Multiple myeloma; Myelodysplastic syndrome; Ovarian cancer; Peritoneal cancer; Solid tumour/cancer70.63
TGFB1P01137Transforming growth factor beta-1 proprotein [Cleaved into: Latency-associated peptide (LAP); Transforming growth factor beta-1 (TGF-beta-1)]Human disease related genesPredicted secreted proteinsArterial occlusive disease; Brain cancer; Idiopathic interstitial pneumonitis; Lesion; Liver cancer; Lung cancer; Osteoarthritis; Pancreatic cancer; Retinopathy; Rheumatoid arthritis; Solid tumour/cancer; Systemic sclerosis200.60
NOTC2Q04721Neurogenic locus notch homolog protein 2 (Notch 2) (hN2) [Cleaved into: Notch 2 extracellular truncation (N2ECD); Notch 2 intracellular domain (N2ICD)]Cancer-related genesDisease related genesHuman disease related genesLung cancer; Pancreatic cancer160.60
EPCAMP16422Epithelial cell adhesion molecule (Ep-CAM) (Adenocarcinoma-associated antigen) (Cell surface glycoprotein Trop-1) (Epithelial cell surface antigen) (Epithelial glycoprotein) (EGP) (Epithelial glycoprotein 314) (EGP314) (hEGP314) (KS 1/4 antigen) (KSA) (Major gastrointestinal tumor-associated protein GA733-2) (Tumor-associated calcium signal transducer 1) (CD antigen CD326)Cancer-related genesCD markersDisease related genesBladder cancer; Breast cancer; Colon cancer; Colorectal cancer; Esophageal cancer; Head and neck cancer; Liver cancer; Lung cancer; Melanoma; Metastatic tumour; Pancreatic cancer; Prostate cancer; Solid tumour/cancer; Stomach cancer40.50
NEPP08473Neprilysin (EC 3.4.24.11) (Atriopeptidase) (Common acute lymphocytic leukemia antigen) (CALLA) (Enkephalinase) (Neutral endopeptidase 24.11) (NEP) (Neutral endopeptidase) (Skin fibroblast elastase) (SFE) (CD antigen CD10)Cancer-related genesCandidate cardiovascular disease genesCD markersAsthma; Cardiovascular disease; Choreiform disorder; Chronic kidney disease; Chronic pain; Heart disease; Heart failure; Hypertension; Hypotension; Intracranial injury; Kidney failure; Leukaemia; Lung cancer; Mature B-cell lymphoma; Multiple sclerosis; Pain; Sexual dysfunction40.50
AA2ARP29274Adenosine receptor A2aCancer-related genesFDA approved drug targetsG-protein coupled receptorsAlzheimer disease; Arterial occlusive disease; Choreiform disorder; Chronic obstructive pulmonary disease; Colorectal cancer; Coronary atherosclerosis; Diabetic foot ulcer; General pain disorder; Glaucoma; Heart failure; Hyper-lipoproteinaemia; Hypertension; Lung cancer; Multiple sclerosis; Orthostatic hypotension; Pain; Parkinsonism; Prostate cancer; Radionuclide imaging; Schizophrenia; Solid tumour/cancer; Unspecific substance use disorder; Vasomotor/allergic rhinitis30.50
ITB1P05556Integrin beta-1 (Fibronectin receptor subunit beta) (Glycoprotein IIa) (GPIIA) (VLA-4 subunit beta) (CD antigen CD29)Cancer-related genesCD markersFDA approved drug targetsBrain cancer; Lung cancer; Retinopathy30.50
PGFRAP16234Platelet-derived growth factor receptor alpha (PDGF-R-alpha) (PDGFR-alpha) (EC 2.7.10.1) (Alpha platelet-derived growth factor receptor) (Alpha-type platelet-derived growth factor receptor) (CD140 antigen-like family member A) (CD140a antigen) (Platelet-derived growth factor alpha receptor) (Platelet-derived growth factor receptor 2) (PDGFR-2) (CD antigen CD140a)Cancer-related genesCD markersDisease related genesAcute myeloid leukaemia; BCR-ABL1-negative chronic myeloid leukaemia; Brain cancer; Breast cancer; Colon cancer; Colorectal cancer; Gastrointestinal stromal tumour; Gram-positive bacterial infection; Kaposi sarcoma; Lung cancer; Malignant digestive organ neoplasm; Mastocytosis; Multiple myeloma; Myelodysplastic syndrome; Pancreatic cancer; Prostate cancer; Solid tumour/cancer; Stomach cancer; Thrombocytopenia30.50
AA2BRP29275Adenosine receptor A2bAlzheimer disease; Asthma; Breathing abnormality; Colorectal cancer; Heart failure; Herpes simplex infection; Hypertension; Ischaemic heart disease; Lung cancer; Multiple sclerosis; Parkinsonism; Solid tumour/cancer; Supraventricular tachyarrhythmia; Type 2 diabetes mellitus20.50
PSCAO43653Prostate stem cell antigenCancer-related genesPredicted intracellular proteinsPredicted membrane proteinsNon-small-cell lung cancer; Pancreatic cancer; Prostate cancer; Solid tumour/cancer; Stomach cancer20.50
ALKQ9UM73ALK tyrosine kinase receptor (EC 2.7.10.1) (Anaplastic lymphoma kinase) (CD antigen CD246)Cancer-related genesCD markersDisease related genesAdrenal cancer; Breast cancer; Colorectal cancer; Diffuse large B-cell lymphoma; Lung cancer; Lymphoma; Mature T-cell lymphoma; Metastatic tumour; Non-small-cell lung cancer; Solid tumour/cancer10.50
EGFRP00533Epidermal growth factor receptor (EC 2.7.10.1) (Proto-oncogene c-ErbB-1) (Receptor tyrosine-protein kinase erbB-1)Cancer-related genesDisease related genesEnzymesAngina pectoris; Brain cancer; Breast cancer; Cerebral ischaemia; Chronic pain; Colon cancer; Colorectal cancer; Cryptosporidiosis; Diabetic foot ulcer; Diffuse large B-cell lymphoma; Digestive system disease; Esophageal cancer; Gram-positive bacterial infection; Head and neck cancer; Hepatitis virus infection; Hypopharyngeal cancer; Intracerebral haemorrhage; Ischemia; Liver cancer; Lung cancer; Lymphoma; Malignant mesenchymal neoplasm; Mature B-cell leukaemia; Melanoma; Metastatic biliary tract neoplasms; Metastatic lymph node neoplasm; Myelodysplastic syndrome; Nasopharyngeal cancer; Non-small-cell lung cancer; Pancreatic cancer; Psoriasis; Renal cell carcinoma; Skin postprocedural disorder; Solid tumour/cancer; Spinal cord/cranial nerve neoplasm; Stomach cancer; Testicular cancer; Unspecific body region injury; Urethral cancer10.50
EGLNP17813Endoglin (CD antigen CD105)Cancer-related genesCandidate cardiovascular disease genesCD markersAngiosarcoma; Brain cancer; Breast cancer; Fallopian tube cancer; Gynecologic cancer; Kaposi sarcoma; Liver cancer; Lung cancer; Non-small-cell lung cancer; Ovarian cancer; Peritoneal cancer; Renal cell carcinoma; Retinopathy10.50
GPC3P51654Glypican-3 (GTR2-2) (Intestinal protein OCI-5) (MXR7) [Cleaved into: Glypican-3 alpha subunit; Glypican-3 beta subunit]Liver cancer; Lung cancer; Metastatic liver/bile duct neoplasm; Solid tumour/cancer10.50
I15RAQ13261Interleukin-15 receptor subunit alpha (IL-15 receptor subunit alpha) (IL-15R-alpha) (IL-15RA) (CD antigen CD215) [Cleaved into: Soluble interleukin-15 receptor subunit alpha (sIL-15 receptor subunit alpha) (sIL-15R-alpha) (sIL-15RA)]CD markersPredicted intracellular proteinsPredicted membrane proteinsAcute myeloid leukaemia; Bladder cancer; Colorectal cancer; Head and neck cancer; Human immunodeficiency virus disease; Lung cancer; Malignant haematopoietic neoplasm; Multiple myeloma; Pancreatic cancer; Solid tumour/cancer10.50
IGF1RP08069Insulin-like growth factor 1 receptor (EC 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) (CD antigen CD221) [Cleaved into: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain]Cancer-related genesCD markersDisease related genesAdrenal cancer; Breast cancer; Chronic kidney disease; Colorectal cancer; Extraocular muscle disorder; Liver cancer; Lung cancer; Motor neuron disease; Multiple myeloma; Multiple structural anomalies syndrome; Pain; Pancreatic cancer; Parkinsonism; Pituitary gland disorder; Retinopathy; Solid tumour/cancer; Thyrotoxicosis10.50
KITP10721Mast/stem cell growth factor receptor Kit (SCFR) (EC 2.7.10.1) (Piebald trait protein) (PBT) (Proto-oncogene c-Kit) (Tyrosine-protein kinase Kit) (p145 c-kit) (v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog) (CD antigen CD117)Cancer-related genesCD markersDisease related genesAcute myeloid leukaemia; Alzheimer disease; Bone/articular cartilage neoplasm; Brain cancer; Colorectal cancer; Gastrointestinal stromal tumour; Inflammatory arthropathy; Liver cancer; Lung cancer; Malignant intestine neoplasm; Mastocytosis; Mature B-cell lymphoma; Multiple myeloma; Myelodysplastic syndrome; Myeloproliferative neoplasm; Phakomatoses/hamartoneoplastic syndrome; Postoperative inflammation; Renal cell carcinoma; Solid tumour/cancer; Thrombocytopenia; Transplanted organ/tissue10.50
MDR1P08183ATP-dependent translocase ABCB1 (ATP-binding cassette sub-family B member 1) (Multidrug resistance protein 1) (EC 7.6.2.2) (P-glycoprotein 1) (Phospholipid transporter ABCB1) (EC 7.6.2.1) (CD antigen CD243)Cancer-related genesCD markersDisease related genesAcute myeloid leukaemia; Adrenal cancer; Bacterial infection; Lung cancer; Ovarian cancer; Solid tumour/cancer10.50
NPT2BO95436Sodium-dependent phosphate transport protein 2B (Sodium-phosphate transport protein 2B) (Na(+)-dependent phosphate cotransporter 2B) (NaPi3b) (Sodium/phosphate cotransporter 2B) (Na(+)/Pi cotransporter 2B) (NaPi-2b) (Solute carrier family 34 member 2)Cancer-related genesDisease related genesHuman disease related genesLung cancer; Ovarian cancer10.50
RASNP01111GTPase NRas (EC 3.6.5.2) (Transforming protein N-Ras)Cancer-related genesDisease related genesEnzymesColorectal cancer; Head and neck cancer; Lung cancer; Pancreatic cancer; Prostate cancer; Solid tumour/cancer10.50

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