Search results
40 records.
- Frequency:
- literature support frequency.
- EVMP score:
- annotation confidence score.
| Protein symbol | UniProt ID | Protein names | Protein classification | Related Diseases | Frequency | EVMP score | Download | |
|---|---|---|---|---|---|---|---|---|
| AA2AR | P29274 | Adenosine receptor A2a | Cancer-related genesFDA approved drug targetsG-protein coupled receptorsPredicted intracellular proteinsPredicted membrane proteinsTransporters | Alzheimer disease; Arterial occlusive disease; Choreiform disorder; Chronic obstructive pulmonary disease; Colorectal cancer; Coronary atherosclerosis; Diabetic foot ulcer; General pain disorder; Glaucoma; Heart failure; Hyper-lipoproteinaemia; Hypertension; Lung cancer; Multiple sclerosis; Orthostatic hypotension; Pain; Parkinsonism; Prostate cancer; Radionuclide imaging; Schizophrenia; Solid tumour/cancer; Unspecific substance use disorder; Vasomotor/allergic rhinitis | 3 | 0.50 | ||
| AA2BR | P29275 | Adenosine receptor A2b | Alzheimer disease; Asthma; Breathing abnormality; Colorectal cancer; Heart failure; Herpes simplex infection; Hypertension; Ischaemic heart disease; Lung cancer; Multiple sclerosis; Parkinsonism; Solid tumour/cancer; Supraventricular tachyarrhythmia; Type 2 diabetes mellitus | 2 | 0.50 | |||
| ALK | Q9UM73 | ALK tyrosine kinase receptor (EC 2.7.10.1) (Anaplastic lymphoma kinase) (CD antigen CD246) | Cancer-related genesCD markersDisease related genesEnzymesFDA approved drug targetsHuman disease related genesPlasma proteinsPredicted intracellular proteinsPredicted membrane proteins | Adrenal cancer; Breast cancer; Colorectal cancer; Diffuse large B-cell lymphoma; Lung cancer; Lymphoma; Mature T-cell lymphoma; Metastatic tumour; Non-small-cell lung cancer; Solid tumour/cancer | 1 | 0.50 | ||
| CD47 | Q08722 | Leukocyte surface antigen CD47 (Antigenic surface determinant protein OA3) (Integrin-associated protein) (IAP) (Protein MER6) (CD antigen CD47) | CD markersPredicted intracellular proteinsPredicted membrane proteinsTransporters | Acute myeloid leukaemia; B-cell lymphoma; Colorectal cancer; Diffuse large B-cell lymphoma; Leukaemia; Lymphoma; Malignant haematopoietic neoplasm; Melanoma; Multiple myeloma; Mycosis fungoides; Myelodysplastic syndrome; Neuroendocrine carcinoma; Non-small-cell lung cancer; Ovarian cancer; Solid tumour/cancer; Squamous cell carcinoma; Stomach cancer | 29 | 0.88 | ||
| CD80 | P33681 | T-lymphocyte activation antigen CD80 (Activation B7-1 antigen) (BB1) (CTLA-4 counter-receptor B7.1) (B7) (CD antigen CD80) | CD markersFDA approved drug targetsPredicted intracellular proteinsPredicted membrane proteins | Diabetes mellitus; Lung cancer; Lymphoma; Rheumatoid arthritis; Solid tumour/cancer; Transplant rejection | 1 | 0.25 | ||
| DAF | P08174 | Complement decay-accelerating factor (CD antigen CD55) | Blood group antigen proteinsCD markersDisease related genesHuman disease related genesPlasma proteinsPredicted intracellular proteinsPredicted membrane proteinsPredicted secreted proteins | Bladder cancer; Brain cancer; Colorectal cancer; Lung cancer; Melanoma; Prostate cancer; Stomach cancer | 34 | 0.63 | ||
| EGFR | P00533 | Epidermal growth factor receptor (EC 2.7.10.1) (Proto-oncogene c-ErbB-1) (Receptor tyrosine-protein kinase erbB-1) | Cancer-related genesDisease related genesEnzymesFDA approved drug targetsHuman disease related genesMetabolic proteinsPlasma proteinsPredicted membrane proteinsPredicted secreted proteinsRAS pathway related proteinsTransporters | Angina pectoris; Brain cancer; Breast cancer; Cerebral ischaemia; Chronic pain; Colon cancer; Colorectal cancer; Cryptosporidiosis; Diabetic foot ulcer; Diffuse large B-cell lymphoma; Digestive system disease; Esophageal cancer; Gram-positive bacterial infection; Head and neck cancer; Hepatitis virus infection; Hypopharyngeal cancer; Intracerebral haemorrhage; Ischemia; Liver cancer; Lung cancer; Lymphoma; Malignant mesenchymal neoplasm; Mature B-cell leukaemia; Melanoma; Metastatic biliary tract neoplasms; Metastatic lymph node neoplasm; Myelodysplastic syndrome; Nasopharyngeal cancer; Non-small-cell lung cancer; Pancreatic cancer; Psoriasis; Renal cell carcinoma; Skin postprocedural disorder; Solid tumour/cancer; Spinal cord/cranial nerve neoplasm; Stomach cancer; Testicular cancer; Unspecific body region injury; Urethral cancer | 1 | 0.50 | ||
| EGLN | P17813 | Endoglin (CD antigen CD105) | Cancer-related genesCandidate cardiovascular disease genesCD markersDisease related genesHuman disease related genesPlasma proteinsPredicted membrane proteins | Angiosarcoma; Brain cancer; Breast cancer; Fallopian tube cancer; Gynecologic cancer; Kaposi sarcoma; Liver cancer; Lung cancer; Non-small-cell lung cancer; Ovarian cancer; Peritoneal cancer; Renal cell carcinoma; Retinopathy | 1 | 0.50 | ||
| EPCAM | P16422 | Epithelial cell adhesion molecule (Ep-CAM) (Adenocarcinoma-associated antigen) (Cell surface glycoprotein Trop-1) (Epithelial cell surface antigen) (Epithelial glycoprotein) (EGP) (Epithelial glycoprotein 314) (EGP314) (hEGP314) (KS 1/4 antigen) (KSA) (Major gastrointestinal tumor-associated protein GA733-2) (Tumor-associated calcium signal transducer 1) (CD antigen CD326) | Cancer-related genesCD markersDisease related genesFDA approved drug targetsHuman disease related genesPlasma proteinsPredicted intracellular proteinsPredicted membrane proteins | Bladder cancer; Breast cancer; Colon cancer; Colorectal cancer; Esophageal cancer; Head and neck cancer; Liver cancer; Lung cancer; Melanoma; Metastatic tumour; Pancreatic cancer; Prostate cancer; Solid tumour/cancer; Stomach cancer | 4 | 0.50 | ||
| EPHB4 | P54760 | Ephrin type-B receptor 4 (EC 2.7.10.1) (Hepatoma transmembrane kinase) (Tyrosine-protein kinase TYRO11) | Cancer-related genesDisease related genesEnzymesHuman disease related genesPlasma proteinsPotential drug targetsPredicted intracellular proteinsPredicted membrane proteinsTransporters | Brain cancer; Cystic/dysplastic kidney disease; Lung cancer; Metastatic meninges neoplasm; Metastatic tumour; Solid tumour/cancer | 2 | 0.25 | ||
| FGFR1 | P11362 | Fibroblast growth factor receptor 1 (FGFR-1) (EC 2.7.10.1) (Basic fibroblast growth factor receptor 1) (BFGFR) (bFGF-R-1) (Fms-like tyrosine kinase 2) (FLT-2) (N-sam) (Proto-oncogene c-Fgr) (CD antigen CD331) | Cancer-related genesCD markersDisease related genesEnzymesFDA approved drug targetsHuman disease related genesPlasma proteinsPredicted intracellular proteinsPredicted membrane proteinsRAS pathway related proteinsTransporters | Acute diabete complication; Acute myeloid leukaemia; Alzheimer disease; Bladder cancer; Breast cancer; Chronic arterial occlusive disease; Colorectal cancer; Coronary atherosclerosis; Endometrial cancer; Epidermal dysplasias; Gram-positive bacterial infection; Idiopathic interstitial pneumonitis; Liver cancer; Lung cancer; Multiple myeloma; Myelodysplastic syndrome; Myeloproliferative neoplasm; Non-alcoholic fatty liver disease; Oesophagitis; Ovarian cancer; Peritoneal cancer; Retina cancer; Solid tumour/cancer; Stomach cancer; Thrombocytopenia; Type 2 diabetes mellitus | 1 | 0.25 | ||
| FOLR1 | P15328 | Folate receptor alpha (FR-alpha) (Adult folate-binding protein) (FBP) (Folate receptor 1) (Folate receptor, adult) (KB cells FBP) (Ovarian tumor-associated antigen MOv18) | Endometrial cancer; Lung cancer; Malaria; Ovarian cancer; Renal cell carcinoma; Solid tumour/cancer | 2 | 0.25 | |||
| GPC3 | P51654 | Glypican-3 (GTR2-2) (Intestinal protein OCI-5) (MXR7) [Cleaved into: Glypican-3 alpha subunit; Glypican-3 beta subunit] | Liver cancer; Lung cancer; Metastatic liver/bile duct neoplasm; Solid tumour/cancer | 1 | 0.50 | |||
| I15RA | Q13261 | Interleukin-15 receptor subunit alpha (IL-15 receptor subunit alpha) (IL-15R-alpha) (IL-15RA) (CD antigen CD215) [Cleaved into: Soluble interleukin-15 receptor subunit alpha (sIL-15 receptor subunit alpha) (sIL-15R-alpha) (sIL-15RA)] | CD markersPredicted intracellular proteinsPredicted membrane proteinsPredicted secreted proteins | Acute myeloid leukaemia; Bladder cancer; Colorectal cancer; Head and neck cancer; Human immunodeficiency virus disease; Lung cancer; Malignant haematopoietic neoplasm; Multiple myeloma; Pancreatic cancer; Solid tumour/cancer | 1 | 0.50 | ||
| IGF1R | P08069 | Insulin-like growth factor 1 receptor (EC 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) (CD antigen CD221) [Cleaved into: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain] | Cancer-related genesCD markersDisease related genesEnzymesFDA approved drug targetsHuman disease related genesPlasma proteinsPredicted intracellular proteinsPredicted membrane proteinsRAS pathway related proteins | Adrenal cancer; Breast cancer; Chronic kidney disease; Colorectal cancer; Extraocular muscle disorder; Liver cancer; Lung cancer; Motor neuron disease; Multiple myeloma; Multiple structural anomalies syndrome; Pain; Pancreatic cancer; Parkinsonism; Pituitary gland disorder; Retinopathy; Solid tumour/cancer; Thyrotoxicosis | 1 | 0.50 | ||
| ITB1 | P05556 | Integrin beta-1 (Fibronectin receptor subunit beta) (Glycoprotein IIa) (GPIIA) (VLA-4 subunit beta) (CD antigen CD29) | Cancer-related genesCD markersFDA approved drug targetsPlasma proteinsPredicted intracellular proteinsPredicted membrane proteinsTransporters | Brain cancer; Lung cancer; Retinopathy | 3 | 0.50 | ||
| KIT | P10721 | Mast/stem cell growth factor receptor Kit (SCFR) (EC 2.7.10.1) (Piebald trait protein) (PBT) (Proto-oncogene c-Kit) (Tyrosine-protein kinase Kit) (p145 c-kit) (v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog) (CD antigen CD117) | Cancer-related genesCD markersDisease related genesEnzymesFDA approved drug targetsHuman disease related genesPlasma proteinsPredicted intracellular proteinsPredicted membrane proteinsRAS pathway related proteins | Acute myeloid leukaemia; Alzheimer disease; Bone/articular cartilage neoplasm; Brain cancer; Colorectal cancer; Gastrointestinal stromal tumour; Inflammatory arthropathy; Liver cancer; Lung cancer; Malignant intestine neoplasm; Mastocytosis; Mature B-cell lymphoma; Multiple myeloma; Myelodysplastic syndrome; Myeloproliferative neoplasm; Phakomatoses/hamartoneoplastic syndrome; Postoperative inflammation; Renal cell carcinoma; Solid tumour/cancer; Thrombocytopenia; Transplanted organ/tissue | 1 | 0.50 | ||
| MARCS | P29966 | Myristoylated alanine-rich C-kinase substrate (MARCKS) (Protein kinase C substrate, 80 kDa protein, light chain) (80K-L protein) (PKCSL) | Plasma proteinsPredicted intracellular proteins | Chronic obstructive pulmonary disease; Lung cancer | 10 | 0.63 | ||
| MDR1 | P08183 | ATP-dependent translocase ABCB1 (ATP-binding cassette sub-family B member 1) (Multidrug resistance protein 1) (EC 7.6.2.2) (P-glycoprotein 1) (Phospholipid transporter ABCB1) (EC 7.6.2.1) (CD antigen CD243) | Cancer-related genesCD markersDisease related genesEnzymesHuman disease related genesMetabolic proteinsPlasma proteinsPredicted intracellular proteinsPredicted membrane proteinsTransporters | Acute myeloid leukaemia; Adrenal cancer; Bacterial infection; Lung cancer; Ovarian cancer; Solid tumour/cancer | 1 | 0.50 | ||
| MET | P08581 | Hepatocyte growth factor receptor (HGF receptor) (EC 2.7.10.1) (HGF/SF receptor) (Proto-oncogene c-Met) (Scatter factor receptor) (SF receptor) (Tyrosine-protein kinase Met) | Cancer-related genesDisease related genesEnzymesFDA approved drug targetsHuman disease related genesPlasma proteinsPredicted intracellular proteinsPredicted membrane proteinsPredicted secreted proteinsRAS pathway related proteinsTransporters | Alzheimer disease; Biliary tract cancer; Brain cancer; Breast cancer; Cardiovascular disease; Chronic arterial occlusive disease; Colorectal cancer; Fibrosis; Glaucoma; Head and neck cancer; Heart disease; Injury; Liver cancer; Liver disease; Lung cancer; Melanoma; Metastatic lymph node neoplasm; Nasopharyngitis; Non-small-cell lung cancer; Ovarian cancer; Renal cell carcinoma; Sarcoma; Solid tumour/cancer; Stomach cancer; Thyroid cancer | 3 | 0.38 | ||
| MSLN | Q13421 | Mesothelin (CAK1 antigen) (Pre-pro-megakaryocyte-potentiating factor) [Cleaved into: Megakaryocyte-potentiating factor (MPF); Mesothelin, cleaved form] | Cancer-related genesDisease related genesPlasma proteinsPredicted intracellular proteinsPredicted membrane proteins | Breast cancer; Cervical cancer; Endometrial cancer; Fallopian tube cancer; Liver cancer; Lung cancer; Lymphatic vessel/lymph nodes disorder; Mesothelial tumour; Mesothelin positive tumour; Metastatic malignant neoplasm; Metastatic pleura neoplasm; Non-small-cell lung cancer; Ovarian cancer; Pancreatic cancer; Peritoneal cancer; Pleural mesothelioma; Solid tumour/cancer; Stomach cancer | 5 | 0.38 | ||
| MUC1 | P15941 | Mucin-1 (MUC-1) (Breast carcinoma-associated antigen DF3) (Cancer antigen 15-3) (CA 15-3) (Carcinoma-associated mucin) (Episialin) (H23AG) (Krebs von den Lungen-6) (KL-6) (PEMT) (Peanut-reactive urinary mucin) (PUM) (Polymorphic epithelial mucin) (PEM) (Tumor-associated epithelial membrane antigen) (EMA) (Tumor-associated mucin) (CD antigen CD227) [Cleaved into: Mucin-1 subunit alpha (MUC1-NT) (MUC1-alpha); Mucin-1 subunit beta (MUC1-beta) (MUC1-CT)] | Cancer-related genesCD markersDisease related genesHuman disease related genesPredicted intracellular proteinsPredicted membrane proteinsPredicted secreted proteins | Acute myeloid leukaemia; Bipolar disorder; Brain cancer; Breast cancer; Cervical cancer; Colorectal cancer; Esophageal cancer; Liver cancer; Lung cancer; Multiple myeloma; Myelodysplastic syndrome; Pancreatic cancer; Solid tumour/cancer; Stomach cancer | 7 | 0.63 | ||
| NEP | P08473 | Neprilysin (EC 3.4.24.11) (Atriopeptidase) (Common acute lymphocytic leukemia antigen) (CALLA) (Enkephalinase) (Neutral endopeptidase 24.11) (NEP) (Neutral endopeptidase) (Skin fibroblast elastase) (SFE) (CD antigen CD10) | Cancer-related genesCandidate cardiovascular disease genesCD markersDisease related genesEnzymesFDA approved drug targetsHuman disease related genesPlasma proteinsPredicted intracellular proteinsPredicted membrane proteins | Asthma; Cardiovascular disease; Choreiform disorder; Chronic kidney disease; Chronic pain; Heart disease; Heart failure; Hypertension; Hypotension; Intracranial injury; Kidney failure; Leukaemia; Lung cancer; Mature B-cell lymphoma; Multiple sclerosis; Pain; Sexual dysfunction | 4 | 0.50 | ||
| NOTC2 | Q04721 | Neurogenic locus notch homolog protein 2 (Notch 2) (hN2) [Cleaved into: Notch 2 extracellular truncation (N2ECD); Notch 2 intracellular domain (N2ICD)] | Cancer-related genesDisease related genesHuman disease related genesPlasma proteinsPredicted intracellular proteinsPredicted membrane proteins | Lung cancer; Pancreatic cancer | 16 | 0.60 | ||
| NOTC3 | Q9UM47 | Neurogenic locus notch homolog protein 3 (Notch 3) [Cleaved into: Notch 3 extracellular truncation; Notch 3 intracellular domain] | Cancer-related genesDisease related genesHuman disease related genesPlasma proteinsPredicted intracellular proteinsPredicted membrane proteins | Lung cancer; Pancreatic cancer | 1 | 0.38 |