Search results
40 records.
- Frequency:
- literature support frequency.
- EVMP score:
- annotation confidence score.
| Protein symbol | UniProt ID | Protein names | Protein classification | Related Diseases | Frequency | EVMP score | Download | |
|---|---|---|---|---|---|---|---|---|
| UFO | P30530 | Tyrosine-protein kinase receptor UFO (EC 2.7.10.1) (AXL oncogene) | Disease related genesEnzymesFDA approved drug targetsPlasma proteinsPredicted membrane proteins | Acute myeloid leukaemia; Breast cancer; Kaposi sarcoma; Lung cancer; Mature B-cell leukaemia; Metastatic malignant neoplasm; Multiple myeloma; Myelodysplastic syndrome; Ovarian cancer; Peritoneal cancer; Solid tumour/cancer | 7 | 0.63 | ||
| TPBG | Q13641 | Trophoblast glycoprotein (5T4 oncofetal antigen) (5T4 oncofetal trophoblast glycoprotein) (5T4 oncotrophoblast glycoprotein) (M6P1) (Wnt-activated inhibitory factor 1) (WAIF1) | Predicted membrane proteins | Breast cancer; Lung cancer; Prostate cancer; Solid tumour/cancer | 1 | 0.25 | ||
| TIGIT | Q495A1 | T-cell immunoreceptor with Ig and ITIM domains (V-set and immunoglobulin domain-containing protein 9) (V-set and transmembrane domain-containing protein 3) | Cervical cancer; Lung cancer; Non-small-cell lung cancer; Solid tumour/cancer | 1 | 0.25 | |||
| TGFR1 | P36897 | TGF-beta receptor type-1 (TGFR-1) (EC 2.7.11.30) (Activin A receptor type II-like protein kinase of 53kD) (Activin receptor-like kinase 5) (ALK-5) (ALK5) (Serine/threonine-protein kinase receptor R4) (SKR4) (TGF-beta type I receptor) (Transforming growth factor-beta receptor type I) (TGF-beta receptor type I) (TbetaR-I) | Disease related genesEnzymesHuman disease related genesPotential drug targetsPredicted intracellular proteinsPredicted membrane proteins | Arterial occlusive disease; Brain cancer; Cachexia; Fibrosis; Idiopathic interstitial pneumonitis; Liver cancer; Lung cancer; Myelodysplastic syndrome; Myeloproliferative neoplasm; Pancreatic cancer; Pulmonary disease; Solid tumour/cancer; Systemic sclerosis; Ureteral cancer | 1 | 0.50 | ||
| TGFB1 | P01137 | Transforming growth factor beta-1 proprotein [Cleaved into: Latency-associated peptide (LAP); Transforming growth factor beta-1 (TGF-beta-1)] | Human disease related genesPredicted secreted proteins | Arterial occlusive disease; Brain cancer; Idiopathic interstitial pneumonitis; Lesion; Liver cancer; Lung cancer; Osteoarthritis; Pancreatic cancer; Retinopathy; Rheumatoid arthritis; Solid tumour/cancer; Systemic sclerosis | 20 | 0.60 | ||
| TACD2 | P09758 | Tumor-associated calcium signal transducer 2 (Cell surface glycoprotein Trop-2) (Membrane component chromosome 1 surface marker 1) (Pancreatic carcinoma marker protein GA733-1) | Disease related genesFDA approved drug targetsHuman disease related genesPredicted membrane proteins | Breast cancer; Non-small-cell lung cancer; Solid tumour/cancer; Ureteral cancer | 16 | 0.72 | ||
| SEM4D | Q92854 | Semaphorin-4D (A8) (BB18) (GR3) (CD antigen CD100) | CD markersPlasma proteinsPredicted intracellular proteinsPredicted membrane proteins | Choreiform disorder; Lung cancer; Metastatic lymph node neoplasm; Multiple sclerosis | 1 | 0.50 | ||
| S39A6 | Q13433 | Zinc transporter ZIP6 (Estrogen-regulated protein LIV-1) (Solute carrier family 39 member 6) (Zrt- and Irt-like protein 6) (ZIP-6) | Metabolic proteinsPredicted membrane proteinsTransporters | Breast cancer; Lung cancer; Non-small-cell lung cancer | 1 | 0.38 | ||
| S1PR1 | P21453 | Sphingosine 1-phosphate receptor 1 (S1P receptor 1) (S1P1) (Endothelial differentiation G-protein coupled receptor 1) (Sphingosine 1-phosphate receptor Edg-1) (S1P receptor Edg-1) (CD antigen CD363) | Cancer-related genesCD markersFDA approved drug targetsG-protein coupled receptorsPredicted membrane proteinsTransporters | Acne vulgaris; Cardiovascular disease; Crohn disease; Cutaneous lupus erythematosus; Diabetes mellitus; Immune system disease; Liver cancer; Lung cancer; Multiple sclerosis; Postoperative inflammation; Psoriasis; Pyoderma gangrenosum; Retinopathy; Rheumatoid arthritis; Solid tumour/cancer; Ulcerative colitis | 1 | 0.25 | ||
| RET | P07949 | Proto-oncogene tyrosine-protein kinase receptor Ret (EC 2.7.10.1) (Cadherin family member 12) (Proto-oncogene c-Ret) [Cleaved into: Soluble RET kinase fragment; Extracellular cell-membrane anchored RET cadherin 120 kDa fragment] | Cancer-related genesDisease related genesEnzymesFDA approved drug targetsHuman disease related genesPlasma proteinsPredicted intracellular proteinsPredicted membrane proteinsTransporters | Breast cancer; Colon cancer; Colorectal cancer; Indeterminate colitis; Lung cancer; Mature B-cell lymphoma; Multiple myeloma; Myelodysplastic syndrome; Neurodegenerative disorder; Solid tumour/cancer; Thrombocytopenia; Thyroid cancer | 1 | 0.38 | ||
| RASN | P01111 | GTPase NRas (EC 3.6.5.2) (Transforming protein N-Ras) | Cancer-related genesDisease related genesEnzymesHuman disease related genesPotential drug targetsPredicted intracellular proteinsRAS pathway related proteins | Colorectal cancer; Head and neck cancer; Lung cancer; Pancreatic cancer; Prostate cancer; Solid tumour/cancer | 1 | 0.50 | ||
| PSCA | O43653 | Prostate stem cell antigen | Cancer-related genesPredicted intracellular proteinsPredicted membrane proteins | Non-small-cell lung cancer; Pancreatic cancer; Prostate cancer; Solid tumour/cancer; Stomach cancer | 2 | 0.50 | ||
| PGFRB | P09619 | Platelet-derived growth factor receptor beta (PDGF-R-beta) (PDGFR-beta) (EC 2.7.10.1) (Beta platelet-derived growth factor receptor) (Beta-type platelet-derived growth factor receptor) (CD140 antigen-like family member B) (Platelet-derived growth factor receptor 1) (PDGFR-1) (CD antigen CD140b) | Cancer-related genesCD markersDisease related genesEnzymesFDA approved drug targetsHuman disease related genesPlasma proteinsPredicted intracellular proteinsPredicted membrane proteinsRAS pathway related proteinsTransporters | Acute diabete complication; Alzheimer disease; Gram-positive bacterial infection; Intracranial injury; Liver cancer; Lung cancer; Multiple myeloma; Myelodysplastic syndrome; Renal cell carcinoma; Solid tumour/cancer; Thrombocytopenia | 1 | 0.25 | ||
| PGFRA | P16234 | Platelet-derived growth factor receptor alpha (PDGF-R-alpha) (PDGFR-alpha) (EC 2.7.10.1) (Alpha platelet-derived growth factor receptor) (Alpha-type platelet-derived growth factor receptor) (CD140 antigen-like family member A) (CD140a antigen) (Platelet-derived growth factor alpha receptor) (Platelet-derived growth factor receptor 2) (PDGFR-2) (CD antigen CD140a) | Cancer-related genesCD markersDisease related genesEnzymesFDA approved drug targetsHuman disease related genesPlasma proteinsPredicted intracellular proteinsPredicted membrane proteinsRAS pathway related proteins | Acute myeloid leukaemia; BCR-ABL1-negative chronic myeloid leukaemia; Brain cancer; Breast cancer; Colon cancer; Colorectal cancer; Gastrointestinal stromal tumour; Gram-positive bacterial infection; Kaposi sarcoma; Lung cancer; Malignant digestive organ neoplasm; Mastocytosis; Multiple myeloma; Myelodysplastic syndrome; Pancreatic cancer; Prostate cancer; Solid tumour/cancer; Stomach cancer; Thrombocytopenia | 3 | 0.50 | ||
| NPT2B | O95436 | Sodium-dependent phosphate transport protein 2B (Sodium-phosphate transport protein 2B) (Na(+)-dependent phosphate cotransporter 2B) (NaPi3b) (Sodium/phosphate cotransporter 2B) (Na(+)/Pi cotransporter 2B) (NaPi-2b) (Solute carrier family 34 member 2) | Cancer-related genesDisease related genesHuman disease related genesMetabolic proteinsPotential drug targetsPredicted membrane proteinsTransporters | Lung cancer; Ovarian cancer | 1 | 0.50 | ||
| NOTC3 | Q9UM47 | Neurogenic locus notch homolog protein 3 (Notch 3) [Cleaved into: Notch 3 extracellular truncation; Notch 3 intracellular domain] | Cancer-related genesDisease related genesHuman disease related genesPlasma proteinsPredicted intracellular proteinsPredicted membrane proteins | Lung cancer; Pancreatic cancer | 1 | 0.38 | ||
| NOTC2 | Q04721 | Neurogenic locus notch homolog protein 2 (Notch 2) (hN2) [Cleaved into: Notch 2 extracellular truncation (N2ECD); Notch 2 intracellular domain (N2ICD)] | Cancer-related genesDisease related genesHuman disease related genesPlasma proteinsPredicted intracellular proteinsPredicted membrane proteins | Lung cancer; Pancreatic cancer | 16 | 0.60 | ||
| NEP | P08473 | Neprilysin (EC 3.4.24.11) (Atriopeptidase) (Common acute lymphocytic leukemia antigen) (CALLA) (Enkephalinase) (Neutral endopeptidase 24.11) (NEP) (Neutral endopeptidase) (Skin fibroblast elastase) (SFE) (CD antigen CD10) | Cancer-related genesCandidate cardiovascular disease genesCD markersDisease related genesEnzymesFDA approved drug targetsHuman disease related genesPlasma proteinsPredicted intracellular proteinsPredicted membrane proteins | Asthma; Cardiovascular disease; Choreiform disorder; Chronic kidney disease; Chronic pain; Heart disease; Heart failure; Hypertension; Hypotension; Intracranial injury; Kidney failure; Leukaemia; Lung cancer; Mature B-cell lymphoma; Multiple sclerosis; Pain; Sexual dysfunction | 4 | 0.50 | ||
| MUC1 | P15941 | Mucin-1 (MUC-1) (Breast carcinoma-associated antigen DF3) (Cancer antigen 15-3) (CA 15-3) (Carcinoma-associated mucin) (Episialin) (H23AG) (Krebs von den Lungen-6) (KL-6) (PEMT) (Peanut-reactive urinary mucin) (PUM) (Polymorphic epithelial mucin) (PEM) (Tumor-associated epithelial membrane antigen) (EMA) (Tumor-associated mucin) (CD antigen CD227) [Cleaved into: Mucin-1 subunit alpha (MUC1-NT) (MUC1-alpha); Mucin-1 subunit beta (MUC1-beta) (MUC1-CT)] | Cancer-related genesCD markersDisease related genesHuman disease related genesPredicted intracellular proteinsPredicted membrane proteinsPredicted secreted proteins | Acute myeloid leukaemia; Bipolar disorder; Brain cancer; Breast cancer; Cervical cancer; Colorectal cancer; Esophageal cancer; Liver cancer; Lung cancer; Multiple myeloma; Myelodysplastic syndrome; Pancreatic cancer; Solid tumour/cancer; Stomach cancer | 7 | 0.63 | ||
| MSLN | Q13421 | Mesothelin (CAK1 antigen) (Pre-pro-megakaryocyte-potentiating factor) [Cleaved into: Megakaryocyte-potentiating factor (MPF); Mesothelin, cleaved form] | Cancer-related genesDisease related genesPlasma proteinsPredicted intracellular proteinsPredicted membrane proteins | Breast cancer; Cervical cancer; Endometrial cancer; Fallopian tube cancer; Liver cancer; Lung cancer; Lymphatic vessel/lymph nodes disorder; Mesothelial tumour; Mesothelin positive tumour; Metastatic malignant neoplasm; Metastatic pleura neoplasm; Non-small-cell lung cancer; Ovarian cancer; Pancreatic cancer; Peritoneal cancer; Pleural mesothelioma; Solid tumour/cancer; Stomach cancer | 5 | 0.38 | ||
| MET | P08581 | Hepatocyte growth factor receptor (HGF receptor) (EC 2.7.10.1) (HGF/SF receptor) (Proto-oncogene c-Met) (Scatter factor receptor) (SF receptor) (Tyrosine-protein kinase Met) | Cancer-related genesDisease related genesEnzymesFDA approved drug targetsHuman disease related genesPlasma proteinsPredicted intracellular proteinsPredicted membrane proteinsPredicted secreted proteinsRAS pathway related proteinsTransporters | Alzheimer disease; Biliary tract cancer; Brain cancer; Breast cancer; Cardiovascular disease; Chronic arterial occlusive disease; Colorectal cancer; Fibrosis; Glaucoma; Head and neck cancer; Heart disease; Injury; Liver cancer; Liver disease; Lung cancer; Melanoma; Metastatic lymph node neoplasm; Nasopharyngitis; Non-small-cell lung cancer; Ovarian cancer; Renal cell carcinoma; Sarcoma; Solid tumour/cancer; Stomach cancer; Thyroid cancer | 3 | 0.38 | ||
| MDR1 | P08183 | ATP-dependent translocase ABCB1 (ATP-binding cassette sub-family B member 1) (Multidrug resistance protein 1) (EC 7.6.2.2) (P-glycoprotein 1) (Phospholipid transporter ABCB1) (EC 7.6.2.1) (CD antigen CD243) | Cancer-related genesCD markersDisease related genesEnzymesHuman disease related genesMetabolic proteinsPlasma proteinsPredicted intracellular proteinsPredicted membrane proteinsTransporters | Acute myeloid leukaemia; Adrenal cancer; Bacterial infection; Lung cancer; Ovarian cancer; Solid tumour/cancer | 1 | 0.50 | ||
| MARCS | P29966 | Myristoylated alanine-rich C-kinase substrate (MARCKS) (Protein kinase C substrate, 80 kDa protein, light chain) (80K-L protein) (PKCSL) | Plasma proteinsPredicted intracellular proteins | Chronic obstructive pulmonary disease; Lung cancer | 10 | 0.63 | ||
| KIT | P10721 | Mast/stem cell growth factor receptor Kit (SCFR) (EC 2.7.10.1) (Piebald trait protein) (PBT) (Proto-oncogene c-Kit) (Tyrosine-protein kinase Kit) (p145 c-kit) (v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog) (CD antigen CD117) | Cancer-related genesCD markersDisease related genesEnzymesFDA approved drug targetsHuman disease related genesPlasma proteinsPredicted intracellular proteinsPredicted membrane proteinsRAS pathway related proteins | Acute myeloid leukaemia; Alzheimer disease; Bone/articular cartilage neoplasm; Brain cancer; Colorectal cancer; Gastrointestinal stromal tumour; Inflammatory arthropathy; Liver cancer; Lung cancer; Malignant intestine neoplasm; Mastocytosis; Mature B-cell lymphoma; Multiple myeloma; Myelodysplastic syndrome; Myeloproliferative neoplasm; Phakomatoses/hamartoneoplastic syndrome; Postoperative inflammation; Renal cell carcinoma; Solid tumour/cancer; Thrombocytopenia; Transplanted organ/tissue | 1 | 0.50 | ||
| ITB1 | P05556 | Integrin beta-1 (Fibronectin receptor subunit beta) (Glycoprotein IIa) (GPIIA) (VLA-4 subunit beta) (CD antigen CD29) | Cancer-related genesCD markersFDA approved drug targetsPlasma proteinsPredicted intracellular proteinsPredicted membrane proteinsTransporters | Brain cancer; Lung cancer; Retinopathy | 3 | 0.50 |