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E.g. CD9; CD81
E.g. CD9 antigen; CD81 antigen
E.g. Brain cancer; Lung cancer
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Supporting publications (n)

Number of publications supporting the inclusion of this protein in EV MemProt Atlas.

EVMP confidence score

Annotation confidence score; open for threshold definitions.

Extremely high >= 0.85High >= 0.70Medium >= 0.55Low >= 0.40
Entry nameUniProt IDProtein namesProtein classificationRelated DiseasesSupporting publications (n)EVMP confidence scoreDownload
SEM4DQ92854Semaphorin-4D (A8) (BB18) (GR3) (CD antigen CD100)CD markersPlasma proteinsPredicted intracellular proteinsChoreiform disorder; Lung cancer; Metastatic lymph node neoplasm; Multiple sclerosis10.50
TGFR1P36897TGF-beta receptor type-1 (TGFR-1) (EC 2.7.11.30) (Activin A receptor type II-like protein kinase of 53kD) (Activin receptor-like kinase 5) (ALK-5) (ALK5) (Serine/threonine-protein kinase receptor R4) (SKR4) (TGF-beta type I receptor) (Transforming growth factor-beta receptor type I) (TGF-beta receptor type I) (TbetaR-I)Disease related genesEnzymesHuman disease related genesArterial occlusive disease; Brain cancer; Cachexia; Fibrosis; Idiopathic interstitial pneumonitis; Liver cancer; Lung cancer; Myelodysplastic syndrome; Myeloproliferative neoplasm; Pancreatic cancer; Pulmonary disease; Solid tumour/cancer; Systemic sclerosis; Ureteral cancer10.50
MSLNQ13421Mesothelin (CAK1 antigen) (Pre-pro-megakaryocyte-potentiating factor) [Cleaved into: Megakaryocyte-potentiating factor (MPF); Mesothelin, cleaved form]Cancer-related genesDisease related genesPlasma proteinsBreast cancer; Cervical cancer; Endometrial cancer; Fallopian tube cancer; Liver cancer; Lung cancer; Lymphatic vessel/lymph nodes disorder; Mesothelial tumour; Mesothelin positive tumour; Metastatic malignant neoplasm; Metastatic pleura neoplasm; Non-small-cell lung cancer; Ovarian cancer; Pancreatic cancer; Peritoneal cancer; Pleural mesothelioma; Solid tumour/cancer; Stomach cancer50.38
METP08581Hepatocyte growth factor receptor (HGF receptor) (EC 2.7.10.1) (HGF/SF receptor) (Proto-oncogene c-Met) (Scatter factor receptor) (SF receptor) (Tyrosine-protein kinase Met)Cancer-related genesDisease related genesEnzymesAlzheimer disease; Biliary tract cancer; Brain cancer; Breast cancer; Cardiovascular disease; Chronic arterial occlusive disease; Colorectal cancer; Fibrosis; Glaucoma; Head and neck cancer; Heart disease; Injury; Liver cancer; Liver disease; Lung cancer; Melanoma; Metastatic lymph node neoplasm; Nasopharyngitis; Non-small-cell lung cancer; Ovarian cancer; Renal cell carcinoma; Sarcoma; Solid tumour/cancer; Stomach cancer; Thyroid cancer30.38
NOTC3Q9UM47Neurogenic locus notch homolog protein 3 (Notch 3) [Cleaved into: Notch 3 extracellular truncation; Notch 3 intracellular domain]Cancer-related genesDisease related genesHuman disease related genesLung cancer; Pancreatic cancer10.38
RETP07949Proto-oncogene tyrosine-protein kinase receptor Ret (EC 2.7.10.1) (Cadherin family member 12) (Proto-oncogene c-Ret) [Cleaved into: Soluble RET kinase fragment; Extracellular cell-membrane anchored RET cadherin 120 kDa fragment]Cancer-related genesDisease related genesEnzymesBreast cancer; Colon cancer; Colorectal cancer; Indeterminate colitis; Lung cancer; Mature B-cell lymphoma; Multiple myeloma; Myelodysplastic syndrome; Neurodegenerative disorder; Solid tumour/cancer; Thrombocytopenia; Thyroid cancer10.38
S39A6Q13433Zinc transporter ZIP6 (Estrogen-regulated protein LIV-1) (Solute carrier family 39 member 6) (Zrt- and Irt-like protein 6) (ZIP-6)Metabolic proteinsPredicted membrane proteinsTransportersBreast cancer; Lung cancer; Non-small-cell lung cancer10.38
EPHB4P54760Ephrin type-B receptor 4 (EC 2.7.10.1) (Hepatoma transmembrane kinase) (Tyrosine-protein kinase TYRO11)Cancer-related genesDisease related genesEnzymesBrain cancer; Cystic/dysplastic kidney disease; Lung cancer; Metastatic meninges neoplasm; Metastatic tumour; Solid tumour/cancer20.25
FOLR1P15328Folate receptor alpha (FR-alpha) (Adult folate-binding protein) (FBP) (Folate receptor 1) (Folate receptor, adult) (KB cells FBP) (Ovarian tumor-associated antigen MOv18)Endometrial cancer; Lung cancer; Malaria; Ovarian cancer; Renal cell carcinoma; Solid tumour/cancer20.25
CD80P33681T-lymphocyte activation antigen CD80 (Activation B7-1 antigen) (BB1) (CTLA-4 counter-receptor B7.1) (B7) (CD antigen CD80)CD markersFDA approved drug targetsPredicted intracellular proteinsDiabetes mellitus; Lung cancer; Lymphoma; Rheumatoid arthritis; Solid tumour/cancer; Transplant rejection10.25
FGFR1P11362Fibroblast growth factor receptor 1 (FGFR-1) (EC 2.7.10.1) (Basic fibroblast growth factor receptor 1) (BFGFR) (bFGF-R-1) (Fms-like tyrosine kinase 2) (FLT-2) (N-sam) (Proto-oncogene c-Fgr) (CD antigen CD331)Cancer-related genesCD markersDisease related genesAcute diabete complication; Acute myeloid leukaemia; Alzheimer disease; Bladder cancer; Breast cancer; Chronic arterial occlusive disease; Colorectal cancer; Coronary atherosclerosis; Endometrial cancer; Epidermal dysplasias; Gram-positive bacterial infection; Idiopathic interstitial pneumonitis; Liver cancer; Lung cancer; Multiple myeloma; Myelodysplastic syndrome; Myeloproliferative neoplasm; Non-alcoholic fatty liver disease; Oesophagitis; Ovarian cancer; Peritoneal cancer; Retina cancer; Solid tumour/cancer; Stomach cancer; Thrombocytopenia; Type 2 diabetes mellitus10.25
PGFRBP09619Platelet-derived growth factor receptor beta (PDGF-R-beta) (PDGFR-beta) (EC 2.7.10.1) (Beta platelet-derived growth factor receptor) (Beta-type platelet-derived growth factor receptor) (CD140 antigen-like family member B) (Platelet-derived growth factor receptor 1) (PDGFR-1) (CD antigen CD140b)Cancer-related genesCD markersDisease related genesAcute diabete complication; Alzheimer disease; Gram-positive bacterial infection; Intracranial injury; Liver cancer; Lung cancer; Multiple myeloma; Myelodysplastic syndrome; Renal cell carcinoma; Solid tumour/cancer; Thrombocytopenia10.25
S1PR1P21453Sphingosine 1-phosphate receptor 1 (S1P receptor 1) (S1P1) (Endothelial differentiation G-protein coupled receptor 1) (Sphingosine 1-phosphate receptor Edg-1) (S1P receptor Edg-1) (CD antigen CD363)Cancer-related genesCD markersFDA approved drug targetsAcne vulgaris; Cardiovascular disease; Crohn disease; Cutaneous lupus erythematosus; Diabetes mellitus; Immune system disease; Liver cancer; Lung cancer; Multiple sclerosis; Postoperative inflammation; Psoriasis; Pyoderma gangrenosum; Retinopathy; Rheumatoid arthritis; Solid tumour/cancer; Ulcerative colitis10.25
TIGITQ495A1T-cell immunoreceptor with Ig and ITIM domains (V-set and immunoglobulin domain-containing protein 9) (V-set and transmembrane domain-containing protein 3)Cervical cancer; Lung cancer; Non-small-cell lung cancer; Solid tumour/cancer10.25
TPBGQ13641Trophoblast glycoprotein (5T4 oncofetal antigen) (5T4 oncofetal trophoblast glycoprotein) (5T4 oncotrophoblast glycoprotein) (M6P1) (Wnt-activated inhibitory factor 1) (WAIF1)Predicted membrane proteinsBreast cancer; Lung cancer; Prostate cancer; Solid tumour/cancer10.25