Browse EV MemProt Atlas
Supporting publications (n)

Number of publications supporting the inclusion of this protein in EV MemProt Atlas.

EVMP confidence score

Annotation confidence score; open for threshold definitions.

Extremely high >= 0.85High >= 0.70Medium >= 0.55Low >= 0.40
UniProt IDProtein namesProtein classificationTransmembrane countRelated DiseasesMediation categoriesDownload
INSRP06213Insulin receptor (IR) (EC 2.7.10.1) (CD antigen CD220) [Cleaved into: Insulin receptor subunit alpha; Insulin receptor subunit beta]CD markersDisease related genesEnzymes1Acute diabete complicationAlzheimer diseaseBreast cancerAdhesion and uptake mediationClinical-translation mediationFusion and delivery mediation60.63
ITB3P05106Integrin beta-3 (Platelet membrane glycoprotein IIIa) (GPIIIa) (CD antigen CD61)Cancer-related genesCD markersDisease related genes1Adhesion and uptake mediationClinical-translation mediationFusion and delivery mediation60.63
KCNN2Q9H2S1Small conductance calcium-activated potassium channel protein 2 (SK2) (SKCa 2) (SKCa2) (KCa2.2)Disease related genesFDA approved drug targetsHuman disease related genes6Multiple myelomaMyelopathyClinical-translation mediationFusion and delivery mediation60.63
MMP15P51511Matrix metalloproteinase-15 (MMP-15) (EC 3.4.24.-) (Membrane-type matrix metalloproteinase 2) (MT-MMP 2) (MTMMP2) (Membrane-type-2 matrix metalloproteinase) (MT2-MMP) (MT2MMP) (SMCP-2)Cancer-related genesEnzymesPlasma proteins1Other mediation60.63
PKD2Q13563Polycystin-2 (PC2) (Autosomal dominant polycystic kidney disease type II protein) (Polycystic kidney disease 2 protein) (Polycystwin) (R48321) (Transient receptor potential cation channel subfamily P member 2)Disease related genesHuman disease related genesPlasma proteins6Fusion and delivery mediationMetabolism mediationReceptor-signaling mediation60.63
SL9A1P19634Sodium/hydrogen exchanger 1 (APNH) (Na(+)/H(+) antiporter, amiloride-sensitive) (Na(+)/H(+) exchanger 1) (NHE-1) (Solute carrier family 9 member 1)Disease related genesHuman disease related genesMetabolic proteins13Angina pectorisCardiac arrhythmiaGenetic cardiac arrhythmiaAdhesion and uptake mediationClinical-translation mediationFusion and delivery mediation60.63
TRPM4Q8TD43Transient receptor potential cation channel subfamily M member 4 (hTRPM4) (Calcium-activated non-selective cation channel 1) (Long transient receptor potential channel 4) (LTrpC-4) (LTrpC4) (Melastatin-4)Disease related genesHuman disease related genesPotential drug targets6Fusion and delivery mediationImmune mediationMetabolism mediation60.63
LPPQ93052Lipoma-preferred partner (LIM domain-containing preferred translocation partner in lipoma)Cancer-related genesDisease related genesHuman disease related genesAdhesion and uptake mediation180.60
NOTC2Q04721Neurogenic locus notch homolog protein 2 (Notch 2) (hN2) [Cleaved into: Notch 2 extracellular truncation (N2ECD); Notch 2 intracellular domain (N2ICD)]Cancer-related genesDisease related genesHuman disease related genes1Lung cancerPancreatic cancerClinical-translation mediationImmune mediationReceptor-signaling mediation160.60
MP2K1Q02750Dual specificity mitogen-activated protein kinase kinase 1 (MAP kinase kinase 1) (MAPKK 1) (MKK1) (EC 2.7.12.2) (ERK activator kinase 1) (MAPK/ERK kinase 1) (MEK 1)Cancer-related genesDisease related genesEnzymesAdhesion and uptake mediationClinical-translation mediationFusion and delivery mediation150.60
WASPP42768Actin nucleation-promoting factor WAS (Wiskott-Aldrich syndrome protein) (WASp)Cancer-related genesDisease related genesHuman disease related genesQualitative platelet defectClinical-translation mediationFusion and delivery mediationImmune mediation150.60
DAB2P98082Disabled homolog 2 (Adaptor molecule disabled-2) (Differentially expressed in ovarian carcinoma 2) (DOC-2) (Differentially-expressed protein 2)Plasma proteinsPredicted intracellular proteinsAdhesion and uptake mediationFusion and delivery mediationReceptor-signaling mediation140.60
E41L1Q9H4G0Band 4.1-like protein 1 (Erythrocyte membrane protein band 4.1-like 1) (Neuronal protein 4.1) (4.1N)Disease related genesHuman disease related genesPredicted intracellular proteinsFusion and delivery mediation140.60
ADH1BP00325All-trans-retinol dehydrogenase [NAD(+)] ADH1B (EC 1.1.1.105) (Alcohol dehydrogenase 1B) (Alcohol dehydrogenase subunit beta)EnzymesFDA approved drug targetsHuman disease related genesClinical-translation mediationMetabolism mediation130.60
NUMBP49757Protein numb homolog (h-Numb) (Protein S171)Cancer-related genesPredicted intracellular proteinsAdhesion and uptake mediationFusion and delivery mediationReceptor-signaling mediation130.60
FBLN5Q9UBX5Fibulin-5 (FIBL-5) (Developmental arteries and neural crest EGF-like protein) (Dance) (Urine p50 protein) (UP50)Disease related genesHuman disease related genesPlasma proteinsAdhesion and uptake mediationImmune mediationMetabolism mediation120.60
GIPC1O14908PDZ domain-containing protein GIPC1 (GAIP C-terminus-interacting protein) (RGS-GAIP-interacting protein) (RGS19-interacting protein 1) (Synectin) (Tax interaction protein 2) (TIP-2)Disease related genesHuman disease related genesPredicted intracellular proteinsFusion and delivery mediationMetabolism mediationReceptor-signaling mediation120.60
NEXNQ0ZGT2Nexilin (F-actin-binding protein) (Nelin)Disease related genesHuman disease related genesPredicted intracellular proteinsAdhesion and uptake mediationFusion and delivery mediation120.60
DSC3Q14574Desmocollin-3 (Cadherin family member 3) (Desmocollin-4) (HT-CP)Disease related genesHuman disease related genesPlasma proteins1Adhesion and uptake mediationImmune mediation110.60
ARHGIQ6ZSZ5Rho guanine nucleotide exchange factor 18 (114 kDa Rho-specific guanine nucleotide exchange factor) (p114-Rho-GEF) (p114RhoGEF) (Septin-associated RhoGEF) (SA-RhoGEF)Disease related genesHuman disease related genesPredicted intracellular proteinsAdhesion and uptake mediationFusion and delivery mediationReceptor-signaling mediation100.50
CAP2P40123Adenylyl cyclase-associated protein 2 (CAP 2)Cancer-related genesPredicted intracellular proteinsFusion and delivery mediation90.50
PLCG1P191741-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 (EC 3.1.4.11) (PLC-148) (Phosphoinositide phospholipase C-gamma-1) (Phospholipase C-II) (PLC-II) (Phospholipase C-gamma-1) (PLC-gamma-1)Cancer-related genesEnzymesMetabolic proteinsClinical-translation mediationFusion and delivery mediationImmune mediation90.50
ARAFP10398Serine/threonine-protein kinase A-Raf (EC 2.7.11.1) (Proto-oncogene A-Raf) (Proto-oncogene A-Raf-1) (Proto-oncogene Pks)EnzymesHuman disease related genesPlasma proteinsClinical-translation mediationReceptor-signaling mediation80.50
ERBB2P04626Receptor tyrosine-protein kinase erbB-2 (EC 2.7.10.1) (Metastatic lymph node gene 19 protein) (MLN 19) (Proto-oncogene Neu) (Proto-oncogene c-ErbB-2) (Tyrosine kinase-type cell surface receptor HER2) (p185erbB2) (CD antigen CD340)Cancer-related genesCD markersDisease related genes1Adhesion and uptake mediationClinical-translation mediationFusion and delivery mediation80.50
G3PP04406Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) (EC 1.2.1.12) (Peptidyl-cysteine S-nitrosylase GAPDH) (EC 2.6.99.-)EnzymesEssential proteinsFDA approved drug targetsMuscular atrophyMuscular dystrophyClinical-translation mediationImmune mediationMetabolism mediation80.50

76-100 of 792 proteins

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