Browse EV MemProt Atlas
Supporting publications (n)

Number of publications supporting the inclusion of this protein in EV MemProt Atlas.

EVMP confidence score

Annotation confidence score; open for threshold definitions.

Extremely high >= 0.85High >= 0.70Medium >= 0.55Low >= 0.40
UniProt IDProtein namesProtein classificationTransmembrane countRelated DiseasesMediation categoriesDownload
CCR2P41597C-C chemokine receptor type 2 (C-C CKR-2) (CC-CKR-2) (CCR-2) (CCR2) (Monocyte chemoattractant protein 1 receptor) (MCP-1-R) (CD antigen CD192)CD markersG-protein coupled receptorsHuman disease related genes7Alzheimer diseaseArterial occlusive diseaseChronic kidney diseaseAdhesion and uptake mediationClinical-translation mediationFusion and delivery mediation30.50
CD3EP07766T-cell surface glycoprotein CD3 epsilon chain (T-cell surface antigen T3/Leu-4 epsilon chain) (CD antigen CD3e)CD markersDisease related genesFDA approved drug targets1Breast cancerMelanomaMycosis fungoidesAdhesion and uptake mediationClinical-translation mediationFusion and delivery mediation30.50
CLCN5P51795H(+)/Cl(-) exchange transporter 5 (Chloride channel protein 5) (ClC-5) (Chloride transporter ClC-5)Disease related genesHuman disease related genesPlasma proteins10Clinical-translation mediationFusion and delivery mediation30.50
CTNB1P35222Catenin beta-1 (Beta-catenin)Cancer-related genesDisease related genesHuman disease related genesColon cancerDesmoid tumourSolid tumour/cancerAdhesion and uptake mediationClinical-translation mediationFusion and delivery mediation30.50
F210BQ96KR6Protein FAM210B, mitochondrialPredicted intracellular proteinsPredicted membrane proteins2Immune mediation30.50
GPC4O75487Glypican-4 (K-glypican) [Cleaved into: Secreted glypican-4]Disease related genesHuman disease related genesPlasma proteinsAdhesion and uptake mediationClinical-translation mediationFusion and delivery mediation30.50
GRP2Q7LDG7RAS guanyl-releasing protein 2 (Calcium and DAG-regulated guanine nucleotide exchange factor I) (CalDAG-GEFI) (Cdc25-like protein) (hCDC25L) (F25B3.3 kinase-like protein)Disease related genesHuman disease related genesPlasma proteinsImmune mediationReceptor-signaling mediation30.50
HS90BP08238Heat shock protein HSP 90-beta (HSP 90) (Heat shock 84 kDa) (HSP 84) (HSP84) (Heat shock protein family C member 3)Cancer-related genesPlasma proteinsPredicted intracellular proteinsClinical-translation mediationImmune mediationMetabolism mediation30.50
ITB1P05556Integrin beta-1 (Fibronectin receptor subunit beta) (Glycoprotein IIa) (GPIIA) (VLA-4 subunit beta) (CD antigen CD29)Cancer-related genesCD markersFDA approved drug targets1Brain cancerLung cancerRetinopathyAdhesion and uptake mediationClinical-translation mediationFusion and delivery mediation30.50
JAK3P52333Tyrosine-protein kinase JAK3 (EC 2.7.10.2) (Janus kinase 3) (JAK-3) (Leukocyte janus kinase) (L-JAK)Cancer-related genesDisease related genesEnzymesAdhesion and uptake mediationClinical-translation mediationImmune mediation30.50
KCC2BQ13554Calcium/calmodulin-dependent protein kinase type II subunit beta (CaM kinase II subunit beta) (CaMK-II subunit beta) (EC 2.7.11.17)Disease related genesEnzymesHuman disease related genesFusion and delivery mediationImmune mediationReceptor-signaling mediation30.50
MCLN1Q9GZU1Mucolipin-1 (ML1) (MG-2) (Mucolipidin) (Transient receptor potential channel mucolipin 1) (TRPML1)Disease related genesHuman disease related genesPotential drug targets6Fusion and delivery mediationMetabolism mediationReceptor-signaling mediation30.50
MRP5O15440ATP-binding cassette sub-family C member 5 (EC 7.6.2.-) (EC 7.6.2.2) (Multi-specific organic anion transporter C) (MOAT-C) (Multidrug resistance-associated protein 5) (SMRP) (pABC11)Cancer-related genesEnzymesMetabolic proteins13Clinical-translation mediationFusion and delivery mediationMetabolism mediation30.50
NMDE2Q13224Glutamate receptor ionotropic, NMDA 2B (GluN2B) (Glutamate [NMDA] receptor subunit epsilon-2) (N-methyl D-aspartate receptor subtype 2B) (NMDAR2B) (NR2B) (N-methyl-D-aspartate receptor subunit 3) (NR3) (hNR3)Disease related genesFDA approved drug targetsHuman disease related genes3Clinical-translation mediationFusion and delivery mediationReceptor-signaling mediation30.50
PDE4AP278153',5'-cyclic-AMP phosphodiesterase 4A (EC 3.1.4.53) (DPDE2) (PDE46) (cAMP-specific phosphodiesterase 4A)EnzymesFDA approved drug targetsMetabolic proteinsAcute upper respiratory infectionAllergic/hypersensitivity disorderAmyloidosisClinical-translation mediationReceptor-signaling mediation30.50
PGAP3Q96FM1GPI-specific phospholipase A2-like PGAP3 (EC 3.1.1.-) (COS16 homolog) (hCOS16) (Gene coamplified with ERBB2 protein) (PER1-like domain-containing protein 1) (Post-GPI attachment to proteins factor 3)Disease related genesHuman disease related genesPredicted intracellular proteins7Metabolism mediation30.50
PGFRAP16234Platelet-derived growth factor receptor alpha (PDGF-R-alpha) (PDGFR-alpha) (EC 2.7.10.1) (Alpha platelet-derived growth factor receptor) (Alpha-type platelet-derived growth factor receptor) (CD140 antigen-like family member A) (CD140a antigen) (Platelet-derived growth factor alpha receptor) (Platelet-derived growth factor receptor 2) (PDGFR-2) (CD antigen CD140a)Cancer-related genesCD markersDisease related genes1Acute myeloid leukaemiaBCR-ABL1-negative chronic myeloid leukaemiaBrain cancerClinical-translation mediationFusion and delivery mediationImmune mediation30.50
PPB1P05187Alkaline phosphatase, placental type (EC 3.1.3.1) (Alkaline phosphatase Regan isozyme) (Placental alkaline phosphatase 1) (PLAP-1)Cancer-related genesEnzymesMetabolic proteins1Fusion and delivery mediation30.50
RIGIO95786Antiviral innate immune response receptor RIG-I (ATP-dependent RNA helicase DDX58) (EC 3.6.4.13) (DEAD box protein 58) (RIG-I-like receptor 1) (RLR-1) (RNA sensor RIG-I) (Retinoic acid-inducible gene 1 protein) (RIG-1) (Retinoic acid-inducible gene I protein) (RIG-I)Disease related genesEnzymesHuman disease related genesClinical-translation mediationFusion and delivery mediationImmune mediation30.50
ROBO2Q9HCK4Roundabout homolog 2Disease related genesHuman disease related genesPlasma proteins1Adhesion and uptake mediation30.50
RPSA2A0A8I5KQE6Small ribosomal subunit protein uS2B (37 kDa laminin receptor precursor) (37LRP) (37/67 kDa laminin receptor) (LRP/LR) (40S ribosomal protein SA) (40S ribosomal protein SA2) (67 kDa laminin receptor) (67LR) (Laminin receptor 1) (LamR) (Laminin-binding protein precursor p40) (LBP/p40)Disease related genesEssential proteinsHuman disease related genesClinical-translation mediationMetabolism mediation30.50
TAUP10636Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)Candidate cardiovascular disease genesDisease related genesFDA approved drug targetsAcute myeloid leukaemiaAlzheimer diseaseCentral nervous system diseaseAdhesion and uptake mediationClinical-translation mediationFusion and delivery mediation30.50
TCHPQ9BT92Trichoplein keratin filament-binding protein (Protein TCHP) (Mitochondrial protein with oncostatic activity) (Mitostatin) (Tumor suppressor protein)Predicted intracellular proteinsFusion and delivery mediation30.50
TNR16P08138Tumor necrosis factor receptor superfamily member 16 (Gp80-LNGFR) (Low affinity neurotrophin receptor p75NTR) (Low-affinity nerve growth factor receptor) (NGF receptor) (Low-affinity nerve growth factor receptor p75NGFR) (Low-affinity nerve growth factor receptor p75NGR) (p75 ICD) (CD antigen CD271)Cancer-related genesCD markersPredicted intracellular proteins1Alzheimer diseaseCerebral ischaemiaChronic painClinical-translation mediationMetabolism mediationReceptor-signaling mediation30.50
4F2P08195Amino acid transporter heavy chain SLC3A2 (4F2 cell-surface antigen heavy chain) (4F2hc) (4F2 heavy chain antigen) (Lymphocyte activation antigen 4F2 large subunit) (Solute carrier family 3 member 2) (CD antigen CD98)Cancer-related genesCD markersEssential proteins1Acute myeloid leukaemiaClinical-translation mediationFusion and delivery mediationImmune mediation20.50

151-175 of 792 proteins

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