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E.g. CD9; CD81
E.g. CD9 antigen; CD81 antigen
E.g. Brain cancer; Lung cancer
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Supporting publications (n)

Number of publications supporting the inclusion of this protein in EV MemProt Atlas.

EVMP confidence score

Annotation confidence score; open for threshold definitions.

Extremely high >= 0.85High >= 0.70Medium >= 0.55Low >= 0.40
Entry nameUniProt IDProtein namesProtein classificationRelated DiseasesSupporting publications (n)EVMP confidence scoreDownload
EPHB4P54760Ephrin type-B receptor 4 (EC 2.7.10.1) (Hepatoma transmembrane kinase) (Tyrosine-protein kinase TYRO11)Cancer-related genesDisease related genesEnzymesBrain cancer; Cystic/dysplastic kidney disease; Lung cancer; Metastatic meninges neoplasm; Metastatic tumour; Solid tumour/cancer20.25
FOLR1P15328Folate receptor alpha (FR-alpha) (Adult folate-binding protein) (FBP) (Folate receptor 1) (Folate receptor, adult) (KB cells FBP) (Ovarian tumor-associated antigen MOv18)Endometrial cancer; Lung cancer; Malaria; Ovarian cancer; Renal cell carcinoma; Solid tumour/cancer20.25
CD80P33681T-lymphocyte activation antigen CD80 (Activation B7-1 antigen) (BB1) (CTLA-4 counter-receptor B7.1) (B7) (CD antigen CD80)CD markersFDA approved drug targetsPredicted intracellular proteinsDiabetes mellitus; Lung cancer; Lymphoma; Rheumatoid arthritis; Solid tumour/cancer; Transplant rejection10.25
FGFR1P11362Fibroblast growth factor receptor 1 (FGFR-1) (EC 2.7.10.1) (Basic fibroblast growth factor receptor 1) (BFGFR) (bFGF-R-1) (Fms-like tyrosine kinase 2) (FLT-2) (N-sam) (Proto-oncogene c-Fgr) (CD antigen CD331)Cancer-related genesCD markersDisease related genesAcute diabete complication; Acute myeloid leukaemia; Alzheimer disease; Bladder cancer; Breast cancer; Chronic arterial occlusive disease; Colorectal cancer; Coronary atherosclerosis; Endometrial cancer; Epidermal dysplasias; Gram-positive bacterial infection; Idiopathic interstitial pneumonitis; Liver cancer; Lung cancer; Multiple myeloma; Myelodysplastic syndrome; Myeloproliferative neoplasm; Non-alcoholic fatty liver disease; Oesophagitis; Ovarian cancer; Peritoneal cancer; Retina cancer; Solid tumour/cancer; Stomach cancer; Thrombocytopenia; Type 2 diabetes mellitus10.25
PGFRBP09619Platelet-derived growth factor receptor beta (PDGF-R-beta) (PDGFR-beta) (EC 2.7.10.1) (Beta platelet-derived growth factor receptor) (Beta-type platelet-derived growth factor receptor) (CD140 antigen-like family member B) (Platelet-derived growth factor receptor 1) (PDGFR-1) (CD antigen CD140b)Cancer-related genesCD markersDisease related genesAcute diabete complication; Alzheimer disease; Gram-positive bacterial infection; Intracranial injury; Liver cancer; Lung cancer; Multiple myeloma; Myelodysplastic syndrome; Renal cell carcinoma; Solid tumour/cancer; Thrombocytopenia10.25
S1PR1P21453Sphingosine 1-phosphate receptor 1 (S1P receptor 1) (S1P1) (Endothelial differentiation G-protein coupled receptor 1) (Sphingosine 1-phosphate receptor Edg-1) (S1P receptor Edg-1) (CD antigen CD363)Cancer-related genesCD markersFDA approved drug targetsAcne vulgaris; Cardiovascular disease; Crohn disease; Cutaneous lupus erythematosus; Diabetes mellitus; Immune system disease; Liver cancer; Lung cancer; Multiple sclerosis; Postoperative inflammation; Psoriasis; Pyoderma gangrenosum; Retinopathy; Rheumatoid arthritis; Solid tumour/cancer; Ulcerative colitis10.25
TIGITQ495A1T-cell immunoreceptor with Ig and ITIM domains (V-set and immunoglobulin domain-containing protein 9) (V-set and transmembrane domain-containing protein 3)Cervical cancer; Lung cancer; Non-small-cell lung cancer; Solid tumour/cancer10.25
TPBGQ13641Trophoblast glycoprotein (5T4 oncofetal antigen) (5T4 oncofetal trophoblast glycoprotein) (5T4 oncotrophoblast glycoprotein) (M6P1) (Wnt-activated inhibitory factor 1) (WAIF1)Predicted membrane proteinsBreast cancer; Lung cancer; Prostate cancer; Solid tumour/cancer10.25
MSLNQ13421Mesothelin (CAK1 antigen) (Pre-pro-megakaryocyte-potentiating factor) [Cleaved into: Megakaryocyte-potentiating factor (MPF); Mesothelin, cleaved form]Cancer-related genesDisease related genesPlasma proteinsBreast cancer; Cervical cancer; Endometrial cancer; Fallopian tube cancer; Liver cancer; Lung cancer; Lymphatic vessel/lymph nodes disorder; Mesothelial tumour; Mesothelin positive tumour; Metastatic malignant neoplasm; Metastatic pleura neoplasm; Non-small-cell lung cancer; Ovarian cancer; Pancreatic cancer; Peritoneal cancer; Pleural mesothelioma; Solid tumour/cancer; Stomach cancer50.38
METP08581Hepatocyte growth factor receptor (HGF receptor) (EC 2.7.10.1) (HGF/SF receptor) (Proto-oncogene c-Met) (Scatter factor receptor) (SF receptor) (Tyrosine-protein kinase Met)Cancer-related genesDisease related genesEnzymesAlzheimer disease; Biliary tract cancer; Brain cancer; Breast cancer; Cardiovascular disease; Chronic arterial occlusive disease; Colorectal cancer; Fibrosis; Glaucoma; Head and neck cancer; Heart disease; Injury; Liver cancer; Liver disease; Lung cancer; Melanoma; Metastatic lymph node neoplasm; Nasopharyngitis; Non-small-cell lung cancer; Ovarian cancer; Renal cell carcinoma; Sarcoma; Solid tumour/cancer; Stomach cancer; Thyroid cancer30.38
NOTC3Q9UM47Neurogenic locus notch homolog protein 3 (Notch 3) [Cleaved into: Notch 3 extracellular truncation; Notch 3 intracellular domain]Cancer-related genesDisease related genesHuman disease related genesLung cancer; Pancreatic cancer10.38
RETP07949Proto-oncogene tyrosine-protein kinase receptor Ret (EC 2.7.10.1) (Cadherin family member 12) (Proto-oncogene c-Ret) [Cleaved into: Soluble RET kinase fragment; Extracellular cell-membrane anchored RET cadherin 120 kDa fragment]Cancer-related genesDisease related genesEnzymesBreast cancer; Colon cancer; Colorectal cancer; Indeterminate colitis; Lung cancer; Mature B-cell lymphoma; Multiple myeloma; Myelodysplastic syndrome; Neurodegenerative disorder; Solid tumour/cancer; Thrombocytopenia; Thyroid cancer10.38
S39A6Q13433Zinc transporter ZIP6 (Estrogen-regulated protein LIV-1) (Solute carrier family 39 member 6) (Zrt- and Irt-like protein 6) (ZIP-6)Metabolic proteinsPredicted membrane proteinsTransportersBreast cancer; Lung cancer; Non-small-cell lung cancer10.38
EPCAMP16422Epithelial cell adhesion molecule (Ep-CAM) (Adenocarcinoma-associated antigen) (Cell surface glycoprotein Trop-1) (Epithelial cell surface antigen) (Epithelial glycoprotein) (EGP) (Epithelial glycoprotein 314) (EGP314) (hEGP314) (KS 1/4 antigen) (KSA) (Major gastrointestinal tumor-associated protein GA733-2) (Tumor-associated calcium signal transducer 1) (CD antigen CD326)Cancer-related genesCD markersDisease related genesBladder cancer; Breast cancer; Colon cancer; Colorectal cancer; Esophageal cancer; Head and neck cancer; Liver cancer; Lung cancer; Melanoma; Metastatic tumour; Pancreatic cancer; Prostate cancer; Solid tumour/cancer; Stomach cancer40.50
NEPP08473Neprilysin (EC 3.4.24.11) (Atriopeptidase) (Common acute lymphocytic leukemia antigen) (CALLA) (Enkephalinase) (Neutral endopeptidase 24.11) (NEP) (Neutral endopeptidase) (Skin fibroblast elastase) (SFE) (CD antigen CD10)Cancer-related genesCandidate cardiovascular disease genesCD markersAsthma; Cardiovascular disease; Choreiform disorder; Chronic kidney disease; Chronic pain; Heart disease; Heart failure; Hypertension; Hypotension; Intracranial injury; Kidney failure; Leukaemia; Lung cancer; Mature B-cell lymphoma; Multiple sclerosis; Pain; Sexual dysfunction40.50
AA2ARP29274Adenosine receptor A2aCancer-related genesFDA approved drug targetsG-protein coupled receptorsAlzheimer disease; Arterial occlusive disease; Choreiform disorder; Chronic obstructive pulmonary disease; Colorectal cancer; Coronary atherosclerosis; Diabetic foot ulcer; General pain disorder; Glaucoma; Heart failure; Hyper-lipoproteinaemia; Hypertension; Lung cancer; Multiple sclerosis; Orthostatic hypotension; Pain; Parkinsonism; Prostate cancer; Radionuclide imaging; Schizophrenia; Solid tumour/cancer; Unspecific substance use disorder; Vasomotor/allergic rhinitis30.50
ITB1P05556Integrin beta-1 (Fibronectin receptor subunit beta) (Glycoprotein IIa) (GPIIA) (VLA-4 subunit beta) (CD antigen CD29)Cancer-related genesCD markersFDA approved drug targetsBrain cancer; Lung cancer; Retinopathy30.50
PGFRAP16234Platelet-derived growth factor receptor alpha (PDGF-R-alpha) (PDGFR-alpha) (EC 2.7.10.1) (Alpha platelet-derived growth factor receptor) (Alpha-type platelet-derived growth factor receptor) (CD140 antigen-like family member A) (CD140a antigen) (Platelet-derived growth factor alpha receptor) (Platelet-derived growth factor receptor 2) (PDGFR-2) (CD antigen CD140a)Cancer-related genesCD markersDisease related genesAcute myeloid leukaemia; BCR-ABL1-negative chronic myeloid leukaemia; Brain cancer; Breast cancer; Colon cancer; Colorectal cancer; Gastrointestinal stromal tumour; Gram-positive bacterial infection; Kaposi sarcoma; Lung cancer; Malignant digestive organ neoplasm; Mastocytosis; Multiple myeloma; Myelodysplastic syndrome; Pancreatic cancer; Prostate cancer; Solid tumour/cancer; Stomach cancer; Thrombocytopenia30.50
AA2BRP29275Adenosine receptor A2bAlzheimer disease; Asthma; Breathing abnormality; Colorectal cancer; Heart failure; Herpes simplex infection; Hypertension; Ischaemic heart disease; Lung cancer; Multiple sclerosis; Parkinsonism; Solid tumour/cancer; Supraventricular tachyarrhythmia; Type 2 diabetes mellitus20.50
PSCAO43653Prostate stem cell antigenCancer-related genesPredicted intracellular proteinsPredicted membrane proteinsNon-small-cell lung cancer; Pancreatic cancer; Prostate cancer; Solid tumour/cancer; Stomach cancer20.50
ALKQ9UM73ALK tyrosine kinase receptor (EC 2.7.10.1) (Anaplastic lymphoma kinase) (CD antigen CD246)Cancer-related genesCD markersDisease related genesAdrenal cancer; Breast cancer; Colorectal cancer; Diffuse large B-cell lymphoma; Lung cancer; Lymphoma; Mature T-cell lymphoma; Metastatic tumour; Non-small-cell lung cancer; Solid tumour/cancer10.50
EGFRP00533Epidermal growth factor receptor (EC 2.7.10.1) (Proto-oncogene c-ErbB-1) (Receptor tyrosine-protein kinase erbB-1)Cancer-related genesDisease related genesEnzymesAngina pectoris; Brain cancer; Breast cancer; Cerebral ischaemia; Chronic pain; Colon cancer; Colorectal cancer; Cryptosporidiosis; Diabetic foot ulcer; Diffuse large B-cell lymphoma; Digestive system disease; Esophageal cancer; Gram-positive bacterial infection; Head and neck cancer; Hepatitis virus infection; Hypopharyngeal cancer; Intracerebral haemorrhage; Ischemia; Liver cancer; Lung cancer; Lymphoma; Malignant mesenchymal neoplasm; Mature B-cell leukaemia; Melanoma; Metastatic biliary tract neoplasms; Metastatic lymph node neoplasm; Myelodysplastic syndrome; Nasopharyngeal cancer; Non-small-cell lung cancer; Pancreatic cancer; Psoriasis; Renal cell carcinoma; Skin postprocedural disorder; Solid tumour/cancer; Spinal cord/cranial nerve neoplasm; Stomach cancer; Testicular cancer; Unspecific body region injury; Urethral cancer10.50
EGLNP17813Endoglin (CD antigen CD105)Cancer-related genesCandidate cardiovascular disease genesCD markersAngiosarcoma; Brain cancer; Breast cancer; Fallopian tube cancer; Gynecologic cancer; Kaposi sarcoma; Liver cancer; Lung cancer; Non-small-cell lung cancer; Ovarian cancer; Peritoneal cancer; Renal cell carcinoma; Retinopathy10.50
GPC3P51654Glypican-3 (GTR2-2) (Intestinal protein OCI-5) (MXR7) [Cleaved into: Glypican-3 alpha subunit; Glypican-3 beta subunit]Liver cancer; Lung cancer; Metastatic liver/bile duct neoplasm; Solid tumour/cancer10.50
I15RAQ13261Interleukin-15 receptor subunit alpha (IL-15 receptor subunit alpha) (IL-15R-alpha) (IL-15RA) (CD antigen CD215) [Cleaved into: Soluble interleukin-15 receptor subunit alpha (sIL-15 receptor subunit alpha) (sIL-15R-alpha) (sIL-15RA)]CD markersPredicted intracellular proteinsPredicted membrane proteinsAcute myeloid leukaemia; Bladder cancer; Colorectal cancer; Head and neck cancer; Human immunodeficiency virus disease; Lung cancer; Malignant haematopoietic neoplasm; Multiple myeloma; Pancreatic cancer; Solid tumour/cancer10.50

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